Tamoxifen suppliers

Tamoxifen

CAS:: 10540-29-1

MF:: C26H29NO

MW:: 371.51

SecurityInformation

Symbol(GHS) ：: GHS08,GHS09

Signal word ：: Danger

Hazard statements ：: H350-H360-H410

Precautionary statements ：: P201-P273-P308+P313

Hazard Codes ：: T,Xi

Risk Statements ：: 45-60-61-64-36/37/38

Safety Statements ：: 53-45-36-26

WGK Germany ：: 3

RTECS ：: KR5919600

HS Code ：: 29221990

Toxicity：: LD50 orl-rat: 4100 mg/kg DRFUD4 9,186,84

Use：: Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

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You can find Tamoxifen suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Shandong Huisheng Import & Export Co., Ltd.