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Palbociclib suppliers
- CAS:
- 571190-30-2
- MF:
- C24H29N7O2
- MW:
- 447.53
Properties
- Melting point::
- 200 ºC
- Boiling point::
- 711.5±70.0 °C(Predicted)
- Density :
- 1.313±0.06 g/cm3(Predicted)
- storage temp. :
- room temp
- solubility :
- Soluble in DMSO (up to 2 mg/ml with warming)
- pka:
- 8.66±0.10(Predicted)
- form :
- powder
- color :
- white to beige
- Stability::
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- InChIKey:
- AHJRHEGDXFFMBM-UHFFFAOYSA-N
- SMILES:
- CC(C1=C(N2C3CCCC3)N=C(NC4=CC=C(N5CCNCC5)C=N4)N=C1)=C(C(C)=O)C2=O
SecurityInformation
- Symbol(GHS) :
-


GHS08,GHS09
- Signal word :
- Warning
- Hazard statements :
- H341-H361f-H373-H411
- Precautionary statements :
- P201-P202-P260-P273-P280-P308+P313
- target organs:
- Bone marrow,male reproductive organs
- WGK Germany :
- WGK 3
- Storage Class:
- 11 - Combustible Solids
- Hazard Classifications:
-
Aquatic Chronic 2
Muta. 2
Repr. 2
STOT RE 2 Oral
- Use:
- Palbociclib (Ibrane(R), Pfizer), a selective CDK4 and CDK6 inhibitor, received accelerated approval from FDA in 2015 for women with estrogen receptor-positive and HER2-negative breast cancer in combination with letrozole.
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