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ChemicalBook >> CAS DataBase List >>Mizoribine

Mizoribine suppliers

Mizoribine

CAS:: 50924-49-7

MF:: C9H13N3O6

MW:: 259.22

SecurityInformation

Symbol(GHS) ：: GHS07,GHS08

Signal word ：: Danger

Hazard statements ：: H315-H319-H335-H360

Precautionary statements ：: P201-P302+P352-P305+P351+P338-P308+P313

Hazard Codes ：: T

Risk Statements ：: 46-60-61-36/37/38

Safety Statements ：: 53-22-26-36/37/39-45

WGK Germany ：: 3

RTECS ：: NI3980000

HS Code ：: 29349990

Toxicity：: LD50 in mice (g/kg): >1.5 i.v., >2.4 i.p. (Mizuno, 1975)

Use：: Mizoribine is a kind of imidazole nucleoside isolated from the culture medium of ascomycetes M-2166 separated from the soil by Japanese scholars Asahi Kasei, being the metabolite which inhibiting the purine synthesis pathway of nucleic acid, mainly being used for inhibiting the rejection reaction before or after renal transplantation and also used for liver transplantation and autoimmune diseases. Mizoribine, as a kind of immunosuppressant, its immunosuppressive effects may be related to its inhibition of purine nucleotide synthesis and increased transcriptional activity of the glucocorticoid receptor. It has been applied at Japanese clinical renal transplantation since December 1991. Many Japanese clinical transplant centers have applied mizoribine as the routine immunization inhibitory drug after kidney transplantation. In recent year, China has also applied kidney transplant anti-rejection drugs for clinical purpose. Mizoribine, compared with similar drugs azathioprine, has a low liver toxicity and bone marrow suppression effect with its main adverse reaction being the gastrointestinal reactions, blood disorders and allergic symptoms, and occasionally bone marrow suppression and acute renal failure.

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You can find Mizoribine suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Apeloa production Co.,Limited

Mizoribine
Remarks: Purity: 0.98|Package: 1g;1.00;USD
TEL: 65400000
CHINA Trader

￥1.00/1g

Capot Chemical Co.,Ltd.

Mizoribine
Remarks: Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
TEL: 571-85586718
CHINA Trader

Henan Tianfu Chemical Co.,Ltd.

Mizoribine
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: +86-0371-55170693
CHINA Trader

career henan chemical co

Mizoribine
Remarks: Purity: 98% | Package: 1KG;1USD
TEL: +86-0371-86658258
CHINA Reagent

￥1.00/1KG

Xiamen AmoyChem Co., Ltd

Mizoribine
TEL: +86-86-5926051114
CHINA Service provider

CONIER CHEM AND PHARMA LIMITED

mizoribine
Remarks: Purity: 0.99 | Package: 1mt
CHINA Trader

Hebei Mojin Biotechnology Co., Ltd

Mizoribine
Remarks: Purity: 99% | Package: 25KG;USD
TEL: +86 13288715578
CHINA Service provider

￥0.00/25KG

TargetMol Chemicals Inc.

Mizoribine；NSC 289637;Bredinin;HE 69
Remarks: Purity: 99.89% | Package: 1 mL * 10mM (in DMSO)；10 mg；100 mg；200 mg；25 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Hefei TNJ Chemical Industry Co.,Ltd.

Mizoribine
TEL: +86-0551-65418671
CHINA Reagent

Shanghai UCHEM Inc.

Bredinin (Mizoribine)
Remarks: Purity: 0.98 | Package: 25G;1G
TEL: +862156762820
CHINA Trader