Mitotan suppliers

Mitotan

CAS:: 53-19-0

MF:: C14H10Cl4

MW:: 320.04

SecurityInformation

Symbol(GHS) ：: GHS08

Signal word ：: Warning

Hazard statements ：: H351

Precautionary statements ：: P280

Hazard Codes ：: Xn

Risk Statements ：: 40

Safety Statements ：: 36/37

RIDADR ：: 3249

WGK Germany ：: 3

RTECS ：: KH7880000

HazardClass ：: 6.1(b)

PackingGroup ：: III

HS Code ：: 2903990002

Use：: Mitotane is an inhibitor of steroidogenesis that suppresses the growth of adrenocortical cells. It blocks the expression of several genes that encode proteins involved in steroidogenesis and disrupts mitochondrial respiratory chain activity in human adrenocortical cells. Mitotane has anti-neoplastic actions, alone or in combination with other compounds, and suppresses cortisol synthesis, although it also has significant toxicity in the gastrointestinal tract and nervous system. It is effective against adrenocortical carcinoma and Cushing’s Syndrome in clinical trials.

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Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd.