Linsitinib suppliers

Linsitinib

CAS:: 867160-71-2

MF:: C26H23N5O

MW:: 421.49

Use：: OSI-906 inhibits tumor growth in an IGF-1R-driven xenograft mouse model, with 100% TGI and 55% regression at a dose of 75 mg/kg and 60% TGI and no regression at a dose of 25 mg/kg. OSI-906 administration induces different elimination half-lives of itself in dog, rat and mice, the elimination half-lives are 1.18 hours, 2.64 hours and 2.14 hours, respectively. OSI-906 administration at different single dose once-daily in femal Sprague-Dawley rat and femal CD-1 mouse reveal that the Vmax is not dose-proportional to OSI-906 dose. OSI-906 elevates the blood glucose levels at a dose of 25 mg/kg after 12 days administration. OSI-906 administration at a single dose of 75 mg/kg in IGF-1R-driven full-length human IGF-1R (LISN) xenograft mouse model achieve maximal inhibition of IGF-1R phosphorylation (80%) between 4 and 24 hours with plasma drug concentrations of 26.6-4.77 μM. OSI-906 administered as a single dose of at 60 mg/kg in NCI-H292 xenografts mice inhibits uptake of glucose at 2, 4, and 24 hours post-treatment in vivo. OSI-906 inhibits the growth of tumors in NCI-H292 xenograft mouse model.

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You can find Linsitinib suppliers, manufacturers, and distributors from countries such as China, United States and the Canada here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Capot Chemical Co.,Ltd.

Cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol
Remarks: Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
TEL: +86-（0）57185586718
CHINA Trader

BOC Sciences

Linsitinib
Remarks: CustNote: Please reach out to us for more information about custom solutions.
TEL: +1-631-485-4226
UNITED STATES Trader

CONIER CHEM AND PHARMA LIMITED

osi-906
Remarks: Purity: 0.99 | Package: 1kg
CHINA Trader

career henan chemical co

Linsitinib
Remarks: Purity: 97%-99% | Package: 1KG;6.68USD
TEL: 0371-86658258
CHINA Trader

$6.68

Dideu Industries Group Limited

Linsitinib
Remarks: Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
TEL: 86-
CHINA Trader

Zhejiang J&C Biological Technology Co.,Limited

Linsitinib
Remarks: Purity: 99% | Package: 5KG;1KG
TEL: 1-+1-2135480471
CHINA Trader

Henan Alfa Chemical Co., Ltd

Linsitinib
Remarks: Purity: 98% | Package: 5g; 25g; 100g; 500g; 1kg; 25kg
CHINA Trader

HANGZHOU LEAP CHEM CO., LTD.

OSI-906
Remarks: Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
TEL: 571-87711850
CHINA Trader

Henan Aochuang Chemical Co.,Ltd.

Linsitinib
Remarks: Purity: 98% | Package: 1KG|10KG|25KG
TEL: +86-0371-63689365
CHINA Trader

TargetMol Chemicals Inc.

Linsitinib；OSI-906
Remarks: Package: 1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Reagent