Fisetin suppliers

Fisetin

CAS:: 528-48-3

MF:: C15H10O6

MW:: 286.24

SecurityInformation

Symbol(GHS) ：: GHS07

Signal word ：: Warning

Hazard statements ：: H315-H319-H335

Precautionary statements ：: P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Risk Statements ：: 36/37/38

Safety Statements ：: 22-24/25

WGK Germany ：: 3

RTECS ：: LK9250000

F ：: 10

TSCA ：: Yes

HS Code ：: 29329990

Use：: Fisetin is a plant polyphenol from the flavonoid group. It occurs in fruits and vegetablesincluding persimmons, strawberries, onions, cucumbers, and apples. It is anantioxidant, exerts anticarcinogenic effects in HCT-116 (human colon carcinoma)cells, and modulates protein kinase and lipid kinase pathways (Wang et al. 2012).Fisetin alter signaling pathway like MAPK, NF-κB, activators of transcription(JAK/STAT), Janus kinase/signal transducers, phosphoinositide-3-kinase-proteinkinase (PI3K/Akt), Wnt, and mammalian target of rapamycin (mTOR), therebyleading to cell cycle arrest in HL-60 cells (human acute promyelocytic leukemiacells) (Singh et al. 2016b). Thus, it exhibits inhibitory effects on adhesion, migration,invasion, and multidrug resistance (Suh et al. 2009).

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Bonerge(Hunan) Lifescience Co., Ltd.