Tetracosactide acetate suppliers

Tetracosactide acetate

CAS:: 16960-16-0

MF:: C136H210N40O31S

MW:: 2933.44

Use：: Cosyntropin (Cortrosyn) is a syntheticpeptide containing the first 24 amino acids of natural corticotropin.Cosyntropin is used as a diagnostic agent to testfor adrenal cortical deficiency. Plasma hydrocortisone concentrationis determined before and 30 minutes after theadministration of 250 g of cosyntropin. Most normal responses result in an approximate doubling of the basalhydrocortisone concentration in 30 to 60 minutes. If the responseis not normal, adrenal insufficiency is indicated.Such adrenal insufficiency could be a result of either adrenalor pituitary malfunction, and further testing is requiredto distinguish between the two. Cosyntropin (250 μg infusedwithin 4–8 hours) or corticotropin (80–120 U/day for3–4 days) is administered. Patients with functional adrenaltissue should respond to this dosage. Patients who respondaccordingly are suspected of hypopituitarism, and the diagnosiscan be confirmed by other tests for pituitary function.Patients who have Addison disease, however, show little orno response.

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Cellmano Biotech Limited