Bufalin suppliers

Bufalin

CAS:: 465-21-4

MF:: C24H34O4

MW:: 386.52

SecurityInformation

Symbol(GHS) ：: GHS06

Signal word ：: Danger

Hazard statements ：: H300

Precautionary statements ：: P301+P310+P330

Hazard Codes ：: T+

Risk Statements ：: 28

Safety Statements ：: 28-36/37-45

RIDADR ：: UN 3462 6.1/PG 2

WGK Germany ：: 3

RTECS ：: EI2962500

HazardClass ：: 6.1(a)

PackingGroup ：: II

HS Code ：: 29322090

Use：: Bufalin is one of the main components of dried secretions of toad which is Bufo , Bufalin has a strong surface anesthetic effect, and it has a long-lasting effect in rabbit cornea and human tongue tests which is stronger than cocaine, about 90 times of cocaine. intravenous fluid Toad (0.05mg/kg) on Anesthetized rabbits , anesthetized rabbits can be caused breathing excitement, cat can also be caused breathe excitement . Its effect is stronger than nikethamide , pentylenetetrazol, lobeline, etc. and it can antagonize morphine respiratory depression. Respiratory stimulant order: Bufalin>Resibufogenin= Cinobufagin =cinobufotaline> Japanese toad toxins. Bufalin low concentrations (10-4) promote release of presynaptic acetylcholine on rat diaphragm , while high concentrations promote first then inhibit, and partly antagonize the neuromuscular blocking effects of Mg2 +,but no inhibition on choline esterase. The above information is edited by the Chemicalbook of Tian Ye.

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Chengdu Biopurify Phytochemicals Ltd.