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Altretamine suppliers

Altretamine

CAS:: 645-05-6

MF:: C9H18N6

MW:: 210.28

SecurityInformation

Symbol(GHS) ：: GHS07

Signal word ：: Warning

Hazard statements ：: H302-H315-H319-H335

Precautionary statements ：: P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

target organs：: Respiratory system

PPE：: dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes ：: Xn

Risk Statements ：: 22-36/37/38

Safety Statements ：: 26-36

WGK Germany ：: 3

RTECS ：: OS1050000

HS Code ：: 2933690000

Storage Class：: 11 - Combustible Solids

Hazard Classifications：: Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Hazardous Substances Data：: 645-05-6(Hazardous Substances Data)

Toxicity：: LD50 in rats, guinea pigs (mg/kg): 350, 255 orally (Jasper)

Use：: Altretamine is available in 50-mg capsules for oraladministration as a second-line treatment for ovarian cancer.The mechanism of action has not been firmly established, althoughthe spectrum of activity is similar to that for otheralkylating agents; however, cross-resistance is not seen.Cytotoxicity has been correlated with metabolism to give thecarbinolamines, which may form imines capable of crosslinking,or decompose to give formaldehyde, which may reactwith nucleophiles on DNA or proteins. The agent is well absorbedupon oral administration, well distributed, and highly(90%) plasma protein bound. The agent is extensively metabolizedin the liver by CYP to give demethylated metabolites via the previously mentioned carbinolamines. Elimination occursprimarily in the urine as mostly demethylated metaboliteswith a terminal elimination half-life of 4 to 10 hours.Myleosuppression and nausea/vomiting are dose-limitingtoxicities. Other adverse effects include lethargy, agitation,hallucinations, skin rash, and elevations in transaminase levels,flulike symptoms, abdominal cramps, and diarrhea.

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You can find Altretamine suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Henan Tianfu Chemical Co.,Ltd.

Altretamine
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: 0371-+86-0371-55170693
CHINA Trader

career henan chemical co

Altretamine
Remarks: Purity: 99% | Package: 1KG;8USD
TEL: 0371-86658258
CHINA Reagent

$8.00

CONIER CHEM AND PHARMA LIMITED

altretamine
Remarks: Purity: 0.99 | Package: 1kg
CHINA Trader

TargetMol Chemicals Inc.

Altretamine
Remarks: Purity: 99.84% | Package: 50mg;30USD|100mg;40USD|200mg;70USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

$30.00

$40.00

$70.00

Hefei Hangang Pharmaceutical Technology Co., Ltd.

Altretamine
Remarks: Purity: 0.99 | Package: 5KG;1KG
CHINA Trader

Hefei TNJ Chemical Industry Co.,Ltd.

altretamine
TEL: 0551-65418671
CHINA Reagent

AFINE CHEMICALS LIMITED

ALTRETAMINE
Remarks: Purity: 99% | Package: USP EP CP
TEL: 571-85134551
CHINA Trader

BOC Sciences

Altretamine
Remarks: Purity: > 98 % | CustNote: Please reach out to us for more information about custom solutions.
TEL: 16314854226
UNITED STATES Reagent

Dayang Chem (Hangzhou) Co.,Ltd.

Altretamine
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Top Quality
TEL: 0571-88938639
CHINA Trader

Shaanxi Didu New Materials Co. Ltd

Altretamine;645-05-6
Remarks: Purity: 0.99 | Package: 25KG,200L
TEL: 86-17392712779
CHINA Trader