Altretamine suppliers

Altretamine

CAS:: 645-05-6

MF:: C9H18N6

MW:: 210.28

SecurityInformation

Symbol(GHS) ：: GHS07

Signal word ：: Warning

Hazard statements ：: H302-H315-H319-H335

Precautionary statements ：: P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

Hazard Codes ：: Xn

Risk Statements ：: 22-36/37/38

Safety Statements ：: 26-36

WGK Germany ：: 3

RTECS ：: OS1050000

HS Code ：: 2933690000

Toxicity：: LD50 in rats, guinea pigs (mg/kg): 350, 255 orally (Jasper)

Use：: Altretamine is available in 50-mg capsules for oraladministration as a second-line treatment for ovarian cancer.The mechanism of action has not been firmly established, althoughthe spectrum of activity is similar to that for otheralkylating agents; however, cross-resistance is not seen.Cytotoxicity has been correlated with metabolism to give thecarbinolamines, which may form imines capable of crosslinking,or decompose to give formaldehyde, which may reactwith nucleophiles on DNA or proteins. The agent is well absorbedupon oral administration, well distributed, and highly(90%) plasma protein bound. The agent is extensively metabolizedin the liver by CYP to give demethylated metabolites via the previously mentioned carbinolamines. Elimination occursprimarily in the urine as mostly demethylated metaboliteswith a terminal elimination half-life of 4 to 10 hours.Myleosuppression and nausea/vomiting are dose-limitingtoxicities. Other adverse effects include lethargy, agitation,hallucinations, skin rash, and elevations in transaminase levels,flulike symptoms, abdominal cramps, and diarrhea.

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You can find Altretamine suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Hebei Mojin Biotechnology Co., Ltd

Altretamine
Remarks: Purity: 99% | Package: 25KG
CHINA Service provider

￥0.00/25KG

Anhui Ruihan Technology Co., Ltd

Altretamine
Remarks: Purity: 99% | Package: 1kg;50USD
CHINA Trader

￥50.00/1kg

Henan Tianfu Chemical Co.,Ltd.

Altretamine
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: 0371-55170693
CHINA Trader

career henan chemical co

Altretamine
Remarks: Purity: 99% | Package: 1KG;8USD
TEL: 0371-86658258
CHINA Reagent

￥8.00/1KG

Hebei Weibang Biotechnology Co., Ltd

Altretamine
Remarks: Purity: 99% | Package: 1KG;10USD
CHINA Trader

￥10.00/1KG

CONIER CHEM AND PHARMA LIMITED

altretamine
Remarks: Purity: 0.99 | Package: 1kg
CHINA Trader

TargetMol Chemicals Inc.

Altretamine；ENT-50852;WR-95704;RB-1515;NSC13875;Hexamethylmelamine
Remarks: Purity: 99.84% | Package: 50mg;30USD|100mg;40USD|200mg;70USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Hubei Ipure Biology Co., Ltd

Altretamine
Remarks: Purity: 0.99 | Package: 5KG;1KG
CHINA Trader

Hefei TNJ Chemical Industry Co.,Ltd.

altretamine
TEL: 0551-65418671
CHINA Reagent

AFINE CHEMICALS LIMITED

ALTRETAMINE
Remarks: Purity: 99% | Package: USP EP CP
TEL: 0571-85134551
CHINA Trader