5-Fluoroorotic acid suppliers

5-Fluoroorotic acid

CAS:: 703-95-7

MF:: C5H3FN2O4

MW:: 174.09

Use：: 5-FOA(5-Fluoroorotic acid ) has become a valuable tool for research in the field of molecular genetics. It has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5'-phosphate decarboxylase deficient. 5-FOA is coverted to 5-fluorouridine monophosphate (5-FUMP) in yeast cells, which can become incorporated into RNA or metabolized to the highly toxic 5-fluoro-2’-deoxyuridine monophosphate (5-FdUMP). 5-FdUMP is a potent inhibitor of thymidylate synthase (TS), causing the cessation of DNA synthesis. More recently, 5-FOA has been shown to possess potent antimalarial activity against both chloroquine-susceptible and chloroquine-resistant clones of Plasmodium falciparum. Studies indicate that TS is the primary target of 5-FOA in malarial parasites. The combination of 5-FOA and uracil has been effective in treating mice infected with Plasmodium yoelli. 5-FOA may also have potential in the treatment of human malarial infections when used in combination with other agents.

More▼

You can find 5-Fluoroorotic acid suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Hebei Weibang Biotechnology Co., Ltd

5-Fluoroorotic acid
Remarks: Purity: 99%|Package: 1kg;1.00;USD
CHINA Trader

￥1.00/1kg

Hebei Chuanghai Biotechnology Co,.LTD

5-Fluoroorotic Acid
Remarks: Purity: 98%|Package: 1KG;10.00;USD
CHINA Trader

￥10.00/1KG

Shanghai Daken Advanced Materials Co.,Ltd

5-Fluoroorotic acid,5-FOA
Remarks: Purity: 99% | Package: 1KG,5KG 10KG
TEL: 371-+86-371-66670886
CHINA Trader

CONIER CHEM AND PHARMA LIMITED

5-fluoroorotic acid
Remarks: Purity: 0.99 | Package: 25kg
CHINA Trader

career henan chemical co

5-Fluoroorotic acid
Remarks: Purity: 99% | Package: 1KG;7USD
TEL: 0371-86658258
CHINA Trader

￥7.00/1KG

TargetMol Chemicals Inc.

5-Fluoroorotic acid
Remarks: Purity: 100% | Package: 50mg;44USD|100mg;66USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
TEL: +1-781-999-5354
UNITED STATES Trader

Hefei TNJ Chemical Industry Co.,Ltd.

5-Fluoroorotic Acid
TEL: 0551-65418671
CHINA Reagent

AFINE CHEMICALS LIMITED

5-FLUOROOROTIC ACID
Remarks: Purity: 99% | Package: USP EP CP
TEL: 0571-85134551
CHINA Trader

Baoji Guokang Bio-Technology Co., Ltd.

5-Fluoroorotic acid
Remarks: Purity: 0.99 | Package: 25KG;10KG;5KG;1KG
TEL: 0917-3909592
CHINA Trader

Dayang Chem (Hangzhou) Co.,Ltd.

5-Fluoroorotic acid
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: High quality
TEL: 571-88938639
CHINA Trader