3,3'-IMINODIPROPIONITRILE suppliers

Properties

Melting point:：

-6 °C

Boiling point:：

205 °C25 mm Hg(lit.)

Density ：

1.02 g/mL at 25 °C(lit.)

refractive index ：

n20/D 1.47(lit.)

Flash point:：

>230 °F

storage temp. ：

2-8°C

pka：

6.13±0.19(Predicted)

form ：

clear liquid

color ：

Colorless to Light yellow to Light orange

Water Solubility ：

Soluble in water.

Stability:：

Stable, but moisture sensitive. Reaction with moisture may lead to a build up of pressure in sealed bottles. Combustible. Incompatible with strong oxidizing agents.

SecurityInformation

Symbol(GHS) ：

GHS07,GHS05,GHS06

Signal word ：

Warning

Hazard statements ：

H315-H319-H301-H318-H335

Precautionary statements ：

P261-P280a-P301+P310a-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes ：

Xi

Risk Statements ：

36/37/38

Safety Statements ：

26

RIDADR ：

UN 3334

WGK Germany ：

2

RTECS ：

UG2975000

TSCA ：

Yes

HS Code ：

29269095

Toxicity：

A neurotoxic synthetic nitrile that causes proximal axonopathies in the spinal cord and brain stem. The proximal axonal swellings are due to interruption of slow axonal transport, resulting in a large accumulation of neurofilaments. Secondary to these effects is a progressive atrophy of the distal axon, secondary demyelination, and gliosis. The slow axonal transport defect appears to be selective, as little evidence for perturbations in fast axonal transport have been reported. Behaviorally, IDPN induces hyperactivity, a “waltzing syndrome,” circling and head-rolling in mice and rats. IDPN intoxication has been advanced as a model for certain motor neuron degenerative diseases such as amyotropic lateral sclerosis (ALS) and hereditary canine spinal muscular atrophy (HCSMA).