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ChemicalBook >> CAS DataBase List >>2-Phenoxyethanol

2-Phenoxyethanol suppliers

2-Phenoxyethanol

CAS:: 122-99-6

MF:: C8H10O2

MW:: 138.16

SecurityInformation

Symbol(GHS) ：: GHS07

Signal word ：: Warning

Hazard statements ：: H302-H319

Precautionary statements ：: P264-P270-P280-P301+P312-P305+P351+P338-P337+P313

Hazard Codes ：: Xn,Xi

Risk Statements ：: 22-36-R36-R22

Safety Statements ：: 26-S26

WGK Germany ：: 1

RTECS ：: KM0350000

Autoignition Temperature：: 535 °C DIN 51794

Hazard Note ：: Irritant

TSCA ：: Yes

HS Code ：: 29094990

Hazardous Substances Data：: 122-99-6(Hazardous Substances Data)

Toxicity：: LD50 orally in Rabbit: 1850 mg/kg LD50 dermal Rabbit > 2000 mg/kg

Use：: Phenoxyethanol produces a local anesthetic effect on the lips, tongue, and other mucous membranes. The pure material is a moderate irritant to the skin and eyes. In animal studies, a 10% v/v solution was not irritant to rabbit skin and a 2% v/v solution was not irritant to the rabbit eye.Long-term exposure to phenoxyethanol may result in CNS toxic effects similar to other organic solvents.Safety issues related to preservatives used in vaccines, including 2-phenoxyethanol have been reviewed.Contact urticaria has been reported upon exposure to 2-phenoxyethanol-containing cosmetics. The US FDA has recommended avoiding at least one topical product containing phenoxyethanol due to concerns over inadvertant exposure to nursing infants. LD50 (rabbit, skin): 5 g/kg LD50 (rat, oral): 1.26 g/kg

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