1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE suppliers

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE

CAS:: 28289-54-5

MF:: C12H15N

MW:: 173.25

SecurityInformation

Symbol(GHS) ：: GHS08,GHS06

Signal word ：: Danger

Hazard statements ：: H370-H301

Precautionary statements ：: P264-P270-P301+P310-P321-P330-P405-P501-P260-P264-P270-P307+P311-P321-P405-P501

Hazard Codes ：: T

Risk Statements ：: 25-39/23/24/25

Safety Statements ：: 45

RIDADR ：: UN 2811 6.1/PG 2

WGK Germany ：: 3

RTECS ：: UT8358900

HazardClass ：: 6.1(b)

PackingGroup ：: III

Toxicity：: Human toxicity originally discovered when it was an unexpected by-product from the illicit synthesis of a heroin substitute (i.e., meperidine analog). Currently used experimentally as the primary animal model for the study of Parkinson’s disease. MPTP is a neurotoxicant that is activated to 1-methyl-4-phenylpyridinium ion (MPP1) by the actions of monoamine oxidase B located in the mitochondria of brain astrocytes. The MPP1 is then transported into dopamine, and to a lesser extent, other monoaminergic neurons. Once inside these dopamine neurons in the substantia nigra, it destroys these neurons by mechanisms that may involve an oxidative cascade and/or inhibition of electron transport. Intoxication causes a parkinsonism syndrome almost identical in signs and symptoms to Parkinson’s disease, including rigidity, bradykinesia, tremor, and postural instability. In the event of known ingestion, immediate (but not delayed) administration of a monoamine oxidase inhibitor (especially one selective for MAO-B like deprenyl) and dopamine uptake inhibitor can be therapeutic.

Use：: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine is a dopaminergic neurotoxin that reportedly causes a severe and irreversible Parkinsonian condition in humans and monkeys.

More▼

You can find 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Henan Tianfu Chemical Co.,Ltd.

C12H15N 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROXPYRIDINE 28289-54-5
Remarks: Purity: 99% | Package: 25KG;5KG;1KG
TEL: 0371-55170693
CHINA Trader

ATK CHEMICAL COMPANY LIMITED

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
Remarks: Purity: 98% HPLC | Package: 5G;10G;25G;50G;100G;250G;1KG
TEL: 21-51877795
CHINA Reagent

career henan chemical co

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
Remarks: Purity: 99% | Package: 1g;1USD
TEL: 0371-86658258
CHINA Trader

￥1.00/1g

PT CHEM GROUP LIMITED

Pyridine,1,2,3,6-tetrahydro-1-methyl-4-phenyl-
Remarks: Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Wholesale price
TEL: 0371-
CHINA Trader