Menadione sodium bisulfite

한글명:Menadione sodium bisulfite

카스 번호130-37-0

상품명:Menadione sodium bisulfite

CBNumberCB9741616

분자식C11H11NaO5S

포뮬러 무게278.25

MOL 파일130-37-0.mol

화학적 성질

녹는점	121-124°C
저장 조건	-20°C
용해도	H2O: ≥50mg/mL, 투명, 무색 ~ 희미한 노란색
InChI	InChI=1S/C11H10O5S.Na.H/c1-11(17(14,15)16)6-9(12)7-4-2-3-5-8(7)10(11)13;;/h2-5H,6H2,1H3,(H,14,15,16);;
InChIKey	JWNUEPMMANLFQO-UHFFFAOYSA-N
SMILES	O=C1C(CC(=O)C2=CC=CC=C12)(C)S(O)(=O)=O.[NaH]
EPA	Menadione sodium bisulfite (130-37-0)

위험 및 안전 성명

위험품 표기	Xi,N
위험 카페고리 넘버	36-50/53-36/38
안전지침서	26-61-60-24/25
유엔번호(UN No.)	UN 3077 9 / PGIII
WGK 독일	3

그림문자(GHS)

Menadione sodium bisulfite 화학적 특성, 용도, 생산

개요
Menadione sodium bisulfite (MSB, also known as vitamin K3), is a crucial growth regulator mediating plant defense response. This substance is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement. This compound and its complex (MSBC) are water-soluble compounds. Menadione and the menadione sodium bisulfite complex are the sources of vitamin K activity in commercial laboratory rodent diets. Menadione possesses high biological activity, but its absorption depends on the amount of fat in the diet. Compared with Menadione, the menadione sodium bisulfite complex is more readily absorbed and is almost as active on a molar basis as phylloquinone. XTT, a tetrazolium salt, could converted to formazan in the presence of an electron coupling reagent such as menadione sodium bisulfite. The formed formazan does not need to be solubilized. Hence, the XTT test, a cytotoxicity evaluation method, is quicker and safer compared with MTT[1-2].
화학적 성질
white powder
용도
Menadione sodium bisulfite has been used:
- as a priming agent in tomato for improving salt tolerance
- to induce reactive oxygen species (ROS) in human lung epithelium BEAS-2B microtissues
- to induce endogenous superoxide production in mouse C17.2 neural stem cells
정의
ChEBI: An organic sodium salt that is the monosodium salt of menadione sulfonate. A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation i vivo.
부작용
Inflammation of the walls of a vein
Facial flushing
Cardiovascular collapse
Severe shock-like reactions
Sweating Injection site reactions
Chest constriction
Pain
Shortness of breath
Bluish discoloration of the skin

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