메틸2-플루오로-3-니트로벤조에이트
한글명:메틸2-플루오로-3-니트로벤조에이트
카스 번호946126-94-9
상품명:methyl 2-fluoro-3-nitrobenzoate
CBNumberCB81553204
분자식C8H6FNO4
포뮬러 무게199.14
MOL 파일946126-94-9.mol
동의어(한글)
메틸2-플루오로-3-니트로벤조에이트
화학적 성질
| 녹는점 | 77- 80° C |
| 끓는 점 | 310.8±27.0 °C(Predicted) |
| 밀도 | 1.388±0.06 g/cm3(Predicted) |
| 저장 조건 | Sealed in dry,Room Temperature |
| 용해도 | 클로로포름(약간 용해됨), 메탄올(약간 용해됨) |
| 물리적 상태 | 고체 |
| 물리적 상태 | 단단한 모양 |
| 색상 | 황백색에서 연한 노란색 |
A solution of 2-fluoro-3-nitrobenzoic acid (5 g, 27.0 mmol) in MeOH (50 mL) was treated with concentrated H2SO4 (1.4 mL, 27.0 mmol) and the resulting reaction was stirred at 50 °C for 16 h. The solvent was removed under reduced pressure and the residue was diluted with EtO Ac. The organic solution was washed with saturated aqueous NaHCO3 solution until the water phase reached neutral pH. The two phases were separated. Organics were washed with water, brine and dried (Na2SO4). The solution was filtered and concentrated to give crude methyl 2-fluoro-3-nitrobenzoate which was used as is in the next step. (5.1 g, 25.2 mmol, 93 %) as a pale yellow solid.