O-ALLYLHYDROXYLAMINE HYDROCHLORIDE

한글명:O-ALLYLHYDROXYLAMINE HYDROCHLORIDE

카스 번호38945-21-0

상품명:O-ALLYLHYDROXYLAMINE HYDROCHLORIDE

CBNumberCB7738618

분자식C3H8ClNO

포뮬러 무게109.55

MOL 파일38945-21-0.mol

화학적 성질

녹는점	~170 °C (dec.)
저장 조건	under inert gas (nitrogen or Argon) at 2-8°C
물리적 상태	powder to crystal
색상	흰색에서 거의 흰색
BRN	3552394
InChIKey	XIQUJVRFXPBMHS-UHFFFAOYSA-N

위험 및 안전 성명

위험품 표기

위험 카페고리 넘버

36/37/38

안전지침서

26-36

WGK 독일

F 고인화성물질

3-9

HS 번호

2928009090

NFPA 704:

	0
2		0

그림문자(GHS)

O-ALLYLHYDROXYLAMINE HYDROCHLORIDE 화학적 특성, 용도, 생산

제조 방법
To a solution of 86.8 gm (1.55 moles) of potassium hydroxide in 330 ml of absolute ethanol is added a solution of 159 gm (1.52 moles) of ethyl N-hydroxycarbamate in 330 ml of absolute ethanol. With external cooling to maintain an internal temperature of 25°C to this mixture is added 195.5 gm (1.62 moles) of allyl bromide. After the addition has been completed, the mixture is heated under reflux for 2 hr. After separating the potassium bromide formed during the reaction and washing it with absolute alcohol, the alcoholic solution is evaporated under reduced pressure. The residue is dissolved in ether and then the ether solution is extracted repeatedly with 10% aqueous sodium hydroxide solution. [From the ether solution, on evaporation 25.5 gm (18%) of ethyl N,O-diallylhydroxycar-bamate, b.p. 91-92°C (8.55 mm Hg) may be isolated.] The aqueous extract is acidified with 10% aqueous sulfuric acid and the ethyl O-allylhy-droxycarbamate is extracted with ether. Upon evaporating the ether off, 134.2 gm (61%) of the intermediate product, b.p. 107°C (12.5 mm Hg), is isolated.
In a steam distillation apparatus, 134 gm of ethyl O-allylhydroxy-carbamate is treated with a solution of 120 gm of potassium hydroxide in 280 ml of water. The product is steam-distilled into a receiver containing dilute hydrochloric acid.
The steam distillate is evaporated under reduced pressure. The residue is taken up twice in absolute ethanol and dried by evaporation under reduced pressure. The yield is 91 gm (55%, overall), m.p. 169-170°C. Upon recrystallization from absolute alcohol and dry ether, the melting point is raised to 170.6-170.8°C (172-174°C). Free O-allylhydrox-ylamine has the following reported properties: b.p. 98-99°C, n²⁵_D 1.4300.
The problems connected with the preparation of O-arylhydroxylamines by this method have been attributed to the instability of the aryl- substituted aminooxy group to the hydrolytic system used in its preparation. This problem has recently been circumvented by substituting for ethyl N-hydroxycarbamate, t-butyl N-hydroxycarbamate.

O-ALLYLHYDROXYLAMINE HYDROCHLORIDE 준비 용품 및 원자재

O-ALLYLHYDROXYLAMINE HYDROCHLORIDE 공급 업체

O-ALLYLHYDROXYLAMINE HYDROCHLORIDE 관련 검색

Send Inquriy