DIBENZYL CARBONATE

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

  H312：피부와 접촉하면 유해함

• 예방조치문구

  P264：취급 후에는 손을 철저히 씻으시오.

  P264：취급 후에는 손을 철저히 씻으시오.

  P270：이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.

  P280：보호장갑/보호의/보안경/안면보호구를 착용하시오.

  P321：(…) 처치를 하시오.

  P501：...에 내용물 / 용기를 폐기 하시오.

DIBENZYL CARBONATE 화학적 특성, 용도, 생산

• 화학적 성질

  Colorless low melting solid

• 용도

  Ionic liquids can effectively accelerate slow N-benzylation reactions utilizing dibenzyl carbonate as an alkylating reagent. Dibenzyl carbonate (DBzlC) has been used to benzylate phenylacetonitrile, benzyl phenylacetate and phenol. Selective N, N-dibenzylation of primary aliphatic amines was carried with dibenzyl carbonate in the presence of phosphonium salts.

• 제조 방법

  To a stirred solution of benzyl alcohol (0.216 g, 2.00 mol), tributylphosphine (0.303 g, 1.50 mmol), and CyTMG (0.394 g, 2.00 mmol) in DMF (2.00 mL), CO2 was added at room temperature. After 15 min, tetrabromomethane (0.663 g, 2.00 mmol) was added, the reaction vessel was sealed, and the contents were stirred for 2 h. Thereafter, the reaction mixture was diluted with ethyl acetate, washed successively with 0.5 m aqueous HCl and saturated aq. NaHCO3 solution, and dried over Na2SO4. Diphenylmetha- nol was added to the organic solution as an internal standard and the yield of dibenzyl carbonate was determined from the relative integrals of a methylene peak of the carbonate and a methine peak of diphenylmethanol in the 1H NMR spectrum of the ethyl acetate solution. Dibenzyl carbonate, prepared by a larger scale reaction of CO2 with benzyl alcohol (1.08 g, 10.0 mmol), was isolated by column chromatography (cyclohexane/ethyl acetate, 50:1) in 67.3% yield (0.816 g).

• 일반 설명

  Dibenzyl carbonate (DBC) is commonly used as a benzylating agent. Dimethyl carbonate and excess of benzyl alcohol undergoes transesterification in the presence of CsF/α-Al₂O₃ (cesium fluoride/aluminum oxide) to form DBC. The formation of N,N-dibenzyl derivatives by the reaction of primary aliphatic amines with DBC in the presence of phosphonium salts has been investigated.

DIBENZYL CARBONATE 준비 용품 및 원자재

DIBENZYL CARBONATE 공급 업체

Global(137)Suppliers

DIBENZYL CARBONATE 관련 검색