P304+P341:들이마신 경우,호흡이 어려운 경우 환자를 신선한 공기가 있는 곳으로 옮기고 호흡하기 편한 자세로 안정을 취하게 함
P342+P311:호흡기 증상이 나타나면 의료기관(의사)의 진찰을 받으시오.
P501:...에 내용물 / 용기를 폐기 하시오.
히알루로니다제 화학적 특성, 용도, 생산
화학적 성질
White or yellowish-white, amorphous powder.
용도
Hyaluronidase from sheep testes has been used:
in flow cytometry
in the isolation of putative spermatogonial stem cells (SSCs)
to study the effects of magnetic stimulation in magnetic hydrogel properties
in immunohistochemistry to visualize collagen type II distribution
to expose group-III auditory neurons of Muller′s organ for patch-clamp recordings
for the degeneration of hydrogels
정의
Any of a class of soluble enzymes produced in mammalian testes that catalyze cleavage of glycosidic
bonds of oartucular mucopolysaccharides. As a
component of venoms, it reduces the viscosity of
connective tissues and promotes tissue penetration
of the ve
일반 설명
Hyaluronidase is a hyaluronic acid-metabolizing enzyme. It is found in the venoms of snake, honeybee and hymenoptera. Hyaluronidase degrades hyaluronic acid (HA), which enhances membrane permeability, lowers viscosity and increases tissue permeability. It enhances the diffusion of local anesthetics, lowers the size of myocardial infarction, improves the effects of anticancer drugs and prevents perineal trauma during spontaneous delivery.
Purification Methods
Hyaluronidase is purified by chromatography on DEAE-cellulose prior to use. [Distler & Jourdain J Biol Chem 248 6772 1973.]