IOP아미돌

한글명:IOP아미돌

카스 번호60166-93-0

상품명:Iopamidol

CBNumberCB5384796

분자식C17H22I3N3O8

포뮬러 무게777.09

MOL 파일60166-93-0.mol

동의어(한글)

IOP아미돌(IOPAMIDOL)

화학적 성질

녹는점	>3200C (dec)
알파	D20 -2.01° (c = 10 in water)
끓는 점	740.14°C (rough estimate)
밀도	2.0203 (estimate)
저장 조건	Keep in dark place,Sealed in dry,2-8°C
용해도	물에 잘 녹고, 메탄올에 아주 약간 녹고, 에탄올(96%)과 염화메틸렌에는 거의 녹지 않습니다.
산도 계수 (pKa)	pKa (25°) 10.70
물리적 상태	Solid
색상	White to off-white
수용성	473.7g/L(25℃)
CAS 데이터베이스	60166-93-0(CAS DataBase Reference)

위험 및 안전 성명

HS 번호	2924296000
유해 물질 데이터	60166-93-0(Hazardous Substances Data)
독성	LD50 in mice, rats, rabbits, dogs (g/kg): 44.5, 28.2, 19.6, 34.7 i.v. (Felder); LD50 in mice (mg iodine/kg body wt): 21,800 i.v.; 20,000 i.p.; 1500 intracerebral (Felder, Pitre).

그림문자(GHS)

IOP아미돌 화학적 특성, 용도, 생산

화학적 성질
White Crystalline Powder
용도
Iopamidol is an organic iodine compound and used as a nonionic radiocontrast medium. Diagnostic aid (radiopaque medium). Iopamidol blocks x-rays as they pass through the body, thereby allowing body structures not containing iodine to be visualized. The degree of opacity produced by iopamidol is directly proportional to the total amount of the iodinated contrast agent in the path of the x-rays. The visualization of body structures is dependent upon the distribution and elimination of iopamidol. (NCI05)
정의
ChEBI: Iopamidol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. It is a benzenedicarboxamide, an organoiodine compound and a pentol.
일반 설명
Iopamidol is a low-osmolar, nonionicmonomer with 49% organically bound iodine. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.
부작용
Arm, back, or jaw pain; blurred vision; chest pain or discomfort; chest tightness or heaviness; confusion; dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position; fast or irregular heartbeat; feeling of warmth; hives; lightheadedness, dizziness, or fainting; nausea; redness of the face, neck, arms, and occasionally, upper chest; slow or irregular heartbeat; sudden sweating; trouble breathing; unusual tiredness or weakness
Mode of action
Iopamidol is a Radiographic Contrast Agent. The mechanism of action of iopamidol is as a X-Ray Contrast Activity.

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