디벤조(A,L)피렌

한글명:디벤조(A,L)피렌

카스 번호191-30-0

상품명:DIBENZO(A,I)PYRENE

CBNumberCB3451069

분자식C24H14

포뮬러 무게302.37

MOL 파일191-30-0.mol

동의어(한글)

다이벤조(A,L)피렌

디벤조(A,L)피렌

화학적 성질

녹는점	228.05°C
끓는 점	378.4°C (rough estimate)
밀도	1.1762 (estimate)
굴절률	1.9130 (estimate)
저장 조건	2-8°C
용해도	클로로포름(아주 약간 용해됨, 가열), 디클로로메탄(약간 용해됨, 가열)
색상	노란색에서 주황색으로
BRN	2054068
안정성	안정적이지만 열에 민감할 수 있으므로 시원하게 유지하세요. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
IARC	2A (Vol. Sup 7, 92) 2010
EPA	Dibenzo[a,l]pyrene (191-30-0)

위험 및 안전 성명

위험품 표기	Xn,T
위험 카페고리 넘버	40-67-36/37/38-45-41-52/53
안전지침서	23-24/25-36/37-45-26-53-39-61
유엔번호(UN No.)	2811
WGK 독일	3
위험 등급	6.1(b)
포장분류	III
유해 물질 데이터	191-30-0(Hazardous Substances Data)

그림문자(GHS)

디벤조(A,L)피렌 화학적 특성, 용도, 생산

화학적 성질
Yellow Solid
용도
An active metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons in hot mix asphalt paving workers. DBC is the most potent tumorigen that has been identified to date. Dib enzo[def,p]chrysene (DBC) is a carcinogen and should be handled with appropriate caution.
일반 설명
Yellow odorless crystals or flakes. Water insoluble.
공기와 물의 반응
Dust/air mixtures may ignite and explode. Insoluble in water.
반응 프로필
Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as DIBENZO(A,I)PYRENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.
Safety Profile
Confirmed carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Carcinogenicity
Dibenzo[a,1]pyrene is a class 2B carcinogen according to the IARC, although recent data suggest that it is a 2A carcinogen. In mouse studies, it has been more potent than benzo[a]pyrene in skin, and in rat studies, it has been more potent than 7,12-dimethylbenz [a]anthracene in the mammary gland. Dibenzo[a,l]pyrene was tested for carcinogenicity in studies of single and repeated dermal application to mice, as well as several initiation–promotion studies on mouse skin; all studies gave positive results. Dibenzo[a,l] pyrene also induced oral cavity tumors when applied dermally to the tongue of hamsters and lung tumors in mice following intraperitoneal injection. In addition to lung tumors, dibenzo[a,l]pyrene induced hepatic tumors and a variety of tumors at other sites when administered intraperitoneally to newborn mice. Multiple tumor sites were also observed following intragastric application of dibenzo[a,l]pyrene in mice. Intramamillary administration to rats also yielded positive results. Furthermore, two studies on fish demonstrated that nonmammalian species are also susceptible to dibenzo[a,l]pyreneinduced tumorigenicity.The most active metabolite is the potent 11,12-dihydrodiol of dibenzo[a,1] pyrene.

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