17-트리플루오로메틸페닐트리노르프로스타글란딘F2ALPHA

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Danger

17-트리플루오로메틸페닐트리노르프로스타글란딘F2ALPHA 화학적 특성, 용도, 생산

• 개요

  A number of 17-phenyl trinor prostaglandin F_2α (17-phenyl trinor PGF_2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF_2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF_2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF_2α is a potent luteolytic and abortifacient, with a potency equal to or greater than fluprostenol and cloprostenol.

17-트리플루오로메틸페닐트리노르프로스타글란딘F2ALPHA 공급 업체

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