gamma-Linolenic acid

한글명:gamma-Linolenic acid

카스 번호506-26-3

상품명:gamma-Linolenic acid

CBNumberCB3238150

분자식C18H30O2

포뮬러 무게278.43

MOL 파일506-26-3.mol

화학적 성질

녹는점	-12～-11℃
끓는 점	379.5±11.0 °C(Predicted)
밀도	0.92
굴절률	n20/D 1.471
인화점	110 °C
저장 조건	-20°C
용해도	클로로포름(난용성), DMSO (약간 용해됨), 메탄올 (약간 용해됨)
물리적 상태	액체
산도 계수 (pKa)	4.74±0.10(Predicted)
색상	무색
Merck	14,5507
BRN	1712253
안정성	감광성
InChIKey	VZCCETWTMQHEPK-QNEBEIHSSA-N
LogP	6.570 (est)
CAS 데이터베이스	506-26-3(CAS DataBase Reference)
NIST	Gamolenic acid(506-26-3)

위험 및 안전 성명

위험품 표기

위험 카페고리 넘버

36/37/38

안전지침서

26-36

WGK 독일

F 고인화성물질

8-10-23

HS 번호

29161500

NFPA 704:

	3
2		0

그림문자(GHS)

gamma-Linolenic acid 화학적 특성, 용도, 생산

개요
γ-Linolenic acid (gamma-linolenic acid or GLA, INN and USAN gamolenic acid) is a fatty acid found primarily in vegetable oils. It is sold as a dietary supplement for treating problems with inflammation and auto-immune diseases, although its efficacy is disputed.
화학적 성질
GLA is categorized as an n?6 (also called ω?6 or omega-6) fatty acid, meaning that the first double bond on the methyl end (designated with n or ω) is the sixth bond. In physiological literature, GLA is designated as 18:3 (n?6). GLA is a carboxylic acid with an 18-carbon chain and three cis double bonds. It is an isomer of α-linolenic acid, which is a polyunsaturated n?3 (omega-3) fatty acid, found in rapeseed canola oil, soy beans, walnuts, flax seed (linseed oil), perilla, chia, and hemp seed.
출처
GLA is obtained from vegetable oils such as GLA safflower oil (Carthamus tinctorius), evening primrose (Oenothera biennis) oil, blackcurrant seed oil, borage oil, and hemp seed oil. GLA is also found in edible hemp seeds, oats, barley, and spirulina. Each contains varying amounts of the fatty acid, with GLA safflower oil at 40% GLA being a novel concentrated form. This is a new genetically modified oil and has been available in commercial quantities since 2011. It should be noted that conventional safflower oils have zero GLA. Borage oil ranges from 15 % to 20 % and evening primrose oil ranges from 8 % to 10 % GLA.
The human body produces GLA from linoleic acid (LA). This reaction is catalyzed by Δ⁶ - desaturase (D6D), an enzyme that allows the creation of a double bond on the sixth carbon counting from the carboxyl terminus. LA is consumed sufficiently in most diets, from such abundant sources as cooking oils and meats. However, a lack of GLA can occur when there is a reduction of the efficiency of the D6D conversion (for instance, as people grow older or when there are specific dietary deficiencies) or in disease states wherein there is excessive consumption of GLA metabolites.
역사
GLA was first isolated from the seed oil of evening primrose. This herbal plant was grown by Native Americans to treat swelling in the body. In the 17th century, it was introduced to Europe and became a popular folk remedy, earning the name king's cure-all. in 1919, Heiduschka and Lüft extracted the oil from evening primrose seeds and described an unusual linolenic acid, which they name γ-. Later, the exact chemical structure was characterized by Riley.
Although there are α- and γ- forms of linolenic acid, there is no β- form. One was once identified, but it turned out to be an artifact of the original analytical process.
용도
γ-Linolenic Acid is a fatty acid found mainly in vegetable oil. Studies suggest that γ-Linolenic Acid may have immune regulating and anti-inflammatory effects. γ-Linolenic Acid has also been used in the treatment of atopic eczeme although its efficacy is
정의
ChEBI: A C18, omega-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.

gamma-Linolenic acid 준비 용품 및 원자재

gamma-Linolenic acid 공급 업체

gamma-Linolenic acid 관련 검색

Send Inquriy