Sodium formaldehydesulfoxylate dihydrate

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H341：유전적인 결함을 일으킬 것으로 의심됨 (노출되어도 생식세포 유전독성을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재)

• 예방조치문구

  P201：사용 전 취급 설명서를 확보하시오.

  P308+P313：노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.

Sodium formaldehydesulfoxylate dihydrate MSDS

• Sodium sulfinomethanolate dihydrate

Sodium formaldehydesulfoxylate dihydrate 화학적 특성, 용도, 생산

• 화학적 성질

  white crystalline powder

• 용도

  Pharmaceutic aid (preservative).

• 생산 방법

  Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.

• 일반 설명

  Oxidation reation of hydroxymethanesulfinic acid with chlorite has been studied in the pH range 4-8. It is a sulfur-containing reducing agent.

• Pharmaceutical Applications

  Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.

• Safety

  The toxicological properties of sodium formaldehyde sulfoxylate have not been fully investigated. However, it is used in the formulation of injection products at a level to 0.1% w/v in the final preparation administered to the patient.
  Sodium formaldehyde sulfoxylate is moderately toxic by ingestion, and when heated to decomposition it emits toxic fumes of sulfur dioxide and sodium oxide.
  LD50 (mouse, oral): 4 g/kg
  LD50 (rat, IP): >2 g/kg
  LD50 (rat, oral): >2 g/kg

• 저장

  Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).

• 비 호환성

  Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.

• Regulatory Status

  Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

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