Butafosfan

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H315：피부에 자극을 일으킴

  H319：눈에 심한 자극을 일으킴

• 예방조치문구

  P264：취급 후에는 손을 철저히 씻으시오.

  P264：취급 후에는 손을 철저히 씻으시오.

  P280：보호장갑/보호의/보안경/안면보호구를 착용하시오.

  P302+P352：피부에 묻으면 다량의 물로 씻으시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

  P321：(…) 처치를 하시오.

  P332+P313：피부 자극이 생기면 의학적인 조치· 조언을 구하시오.

  P362：오염된 의복을 벗고 세척 후에 재사용하기

Butafosfan 화학적 특성, 용도, 생산

• 화학적 성질

  Butafosfan is a white crystalline powder, very easily is dissolved in water. soluble in organic solvents such as ethanol, which should be purged with an inert gas. The solubility of butafosfan in ethanol is approximately 1 mg/ml. It has the effect that improves energy metabolism and strengthen immunologic function.

• 용도

  Butafosfan is an organic phosphorus supplement that is given, most commonly with cyanocobalamin, to cattle, swine, horses, and poultry for the prevention or treatment of deficiencies. When given with cyanocobalamin, butafosfan alters lipid metabolism, serving to decrease the prevalence of subclinical ketosis.

• benefits

  Butafosfan works by increasing the body's ability to metabolise glucose and other nutrients, as well as supporting the production of adenosine triphosphate, which is the main source of cellular energy. Cyanocobalamin, a form of vitamin B12, is essential for normal nerve function and red blood cell formation.

• Mechanism of action

  Butafosfan works by improving the body’s ability to metabolize glucose and other nutrients, as well as by supporting the production of ATP, which is the primary source of energy for cells. The association of Butafosfan and cyanocobalamin could favors the phosphorylation of molecules that intermediate metabolic pathways, such as a gluconeogenesis, glycolysis, and the Krebs cycle, improving the synthesis of the co-nutrients (ATP and ADP mainly) and consequently increasing blood glucose. However, it is still unclear if these results refer mainly to one of the nutrients, Butafosfan or cyanocobalamin[1].
  

• Toxicity evaluation

  The acute toxicity of butafosfan is very low. The oral LD50 in mice was approximately 16 000 mg/kg bw. After parenteral administrations, the following LD50 values were obtained in mice: approximately 21 000 mg/kg bw (subcutaneously), approximately 10 000 mg/kg bw (intravenously) and greater than 2500 mg/kg bw (intraperitoneally). Mice dosed orally or subcutaneously died within 3 and 2 days, respectively, while survivors had recovered by that time. The LD50 value in chicken (intramuscularly) was 9974 mg/kg bw. Observed toxic signs were excitation, cyanosis, sternal recumbency and diarrhoea.

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