3-METHYL-1H-INDAZOLE

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

  H315：피부에 자극을 일으킴

  H317：알레르기성 피부 반응을 일으킬 수 있음

  H319：눈에 심한 자극을 일으킴

  H335：호흡 자극성을 일으킬 수 있음

• 예방조치문구

  P261：분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.

  P280：보호장갑/보호의/보안경/안면보호구를 착용하시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

3-METHYL-1H-INDAZOLE 화학적 특성, 용도, 생산

• 용도

  3-Methyl-1H-indazole is an intermediate compound. It can be used as an organic synthesis reagent for the preparation of 3-methyl-1H-indazol-5-amine and 3-methyl-5-nitro-1H-indazole compounds. In addition, the 3-Methyl-1H-indazole derivatives (1a-1d and 2a-2d) have antimicrobial effects, both having antibacterial activity against Bacillus subtilis and Escherichia coli^[1].

• Synthesis Reference(s)

  Journal of Heterocyclic Chemistry, 25, p. 1817, 1988 DOI: 10.1002/jhet.5570250641
  Synthesis, p. 982, 1984

• 참고 문헌

  [1] FARRUKH SHAIKH. Synthesis and evaluation of antibacterial activity of novel 3-methyl-1H-indazole derivatives[J]. Intelligent Pharmacy, 2024. DOI:10.1016/j.ipha.2023.09.003.

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