ニザチジン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P301+P312：飲み込んだ場合：気分が悪い時は医師に連絡する こと。

  P501：内容物/容器を．．．に廃棄すること。

ニザチジン 価格

MSDS Information

• Nizatidine

ニザチジン 化学特性,用途語,生産方法

• 外観

  白色～うすい黄色粉末～結晶

• 用途

  ヒスタミンH2 受容体遮断剤 です。胃粘膜のヒスタミンH2受容体を遮断し、 胃酸分泌を抑制作用を示します。

• 効能

  消化性潰瘍薬, H2受容体拮抗薬

• 商品名

  アシノン (ゼリア新薬工業)

• 説明

  Nizatidine is the fifth H₂-antagonist introduced to the world market as an antiulcer agent. It is reported to be effective in the treatment of both duodenal and gastric ulcers or the prevention of their recurrences. Given once-daily, nizatidine’s bioavailability is not diminished by the concurrent administration of an antacid.

• 化学的特性

  White Crystalline Powder

• 使用

  Nizatidine is used for treating stomach and duodenum ulcers and other conditions accompanied by elevated acidity of the gastrointestinal tract.

• 適応症

  Nizatidine is the newest H2-receptor antagonist. Similar to ranitidine, it has a relative potency twice that of cimetidine.About 90% of an oral dose is absorbed, with a peak plasma concentration occurring after 0.5 to 3 hours; inhibition of gastric secretion is present for up to 10 hours.The elimination half-life is 1 to 2 hours, and more than 90% of an oral dose is excreted in the urine.

• 定義

  ChEBI: A member of the class of 1,3-thiazoles having a dimethylaminomethyl substituent at position 2 and an alkylthiomethyl moiety at position 4.

• 一般的な説明

  Nizatidine, N-[2-[[[2-(dimethylamino)methyl]-4-thiazolyl]methyl]thio]-ethyl]-N'-methyl-2-nitro-1,1-ethenediamine (Axid), is an off-white to buff crystallinesolid that is soluble in water, alcohol, and chloroform. It isa thaizole derivative of raniditine and has pKas of 2.1 (side chain) and 6.8 (dimethylamino). Nizatidine’s mechanism ofaction is similar to other H₂-antagonists, as is its receptor selectivity.It is more potent than cimetidine.
  Nizatidine has excellent oral bioavailability (＞90%).The effects of antacids or food on its bioavailability arenot clinically significant. The elimination half-life is 1 to2 hours. It is excreted primarily in the urine (90%) andmostly as unchanged drug (60%). Metabolites include nizatidinesulfoxide (6%), N-desmethylnizatidine (7%), andnizatidine N-oxide (dimethylaminomethyl function).Nizatidine has no demonstrable antiandrogenic action, effectson other hormones, or inhibitory effects on cytochromeisozymes involved in the metabolism of other drugs.

ニザチジン 上流と下流の製品情報

ニザチジン 生産企業

Global(372)Suppliers

ニザチジン スペクトルデータ(¹HNMR)

76963-41-2, ニザチジン キーワード