メステロロン

化学名:メステロロン

CAS番号.1424-00-6

英語名:Mesterolone

CBNumberCB9691874

MFC20H32O2

MW304.47

MOL File1424-00-6.mol

别名

1α-メチルアンドロスタン-17β-オール-3-オン

メステロロン

1α-メチル-17β-ヒドロキシ-5α-アンドロスタン-3-オン

メステロロン物理性質

融点	208 °C
比旋光度	D20 +17.6° (c = 0.875 in CHCl3)
沸点	420.3±45.0 °C(Predicted)
比重(密度)	1.156 g/cm3
屈折率	17.6 ° (C=0.9, CHCl3)
貯蔵温度	2-8°C
溶解性	水にほとんど溶けず、アセトン、酢酸エチル、メタノールにやや溶けにくい
酸解離定数(Pka)	15.09±0.70(Predicted)
水溶解度	3mg/L at 20℃
Merck	5916
InChI	InChI=1/C20H32O2/c1-12-10-14(21)11-13-4-5-15-16-6-7-18(22)19(16,2)9-8-17(15)20(12,13)3/h12-13,15-18,22H,4-11H2,1-3H3/t12-,13-,15-,16-,17-,18-,19-,20-/s3
InChIKey	UXYRZJKIQKRJCF-TZPFWLJSSA-N
SMILES	[C@@]12([H])CC[C@@]3([H])CC(=O)C[C@H](C)[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O \|&1:0,4,10,12,14,18,20,23,r\|
CAS データベース	1424-00-6(CAS DataBase Reference)

安全性情報

主な危険性	Xn,T,F
Rフレーズ	20/21/22-38-19-11-61-60
Sフレーズ	22-24/25-36/37/39-45-53
WGK Germany	3
RTECS 番号	BV8063400
HSコード	29372900
DEA Controlled Substances	CSCN: 4000 CSA SCH: Schedule III NARC: No

危険有害性情報のコード(GHS)

メステロロン価格

製品番号	包装	価格	製品説明	購入
東京化成工業 M1800	1g	￥11400	1α-メチルアンドロスタン-17β-オール-3-オン >98.0%(HPLC)	購入
Sigma-Aldrich Japan M7655	100mg	￥19700	analytical standard	購入

MSDS Information

メステロロン化学特性,用途語,生産方法

効能
タンパク同化薬, アンドロゲン受容体作動薬
説明
Mesterolone (Item No. 21171) is an analytical reference standard categorized as an anabolic androgenic steroid. Formulations containing mesterolone have been used in patients with low testosterone or symptoms of aging male syndrome. Mesterolone cannot be aromatized to estrogens, unlike other androgens. This compound is the active ingredient in different pharmaceutical preparations that have been used medically but have also been widely applied in sports in order to improve athlete performance. Mesterolone is regulated as a Schedule III drug in the United States. This product is intended for research and forensic applications.
化学的特性
White or yellowish crystalline powder.
使用
Mesterolone is a synthetic androgen and a dihydrotestosterone derivative. Mesterolone is rarely used for replacement therapies due to its weak androgenic activity.
定義
ChEBI: Mesterolone is a 3-oxo-5alpha-steroid. It is a structurally altered DHT hormone possessing the addition of a methyl group at the carbon one position. This allows the hormone to survive oral ingestion by protecting it from hepatic breakdown. This is one of the only oral anabolic steroids that is not C17-alpha alkylated (C17-aa) but instead carries the added methyl group.
主な応用
Mesterolone is a pharmacological agent that belongs to the group of androgens. It is an oral preparation and has been used in the treatment of infectious diseases, autoimmune diseases, and metabolic disorders. It has also been used as a matrix effect control in biological samples. The biological effects of it are mediated by its direct action on cells or through conversion to testosterone or dihydrotestosterone (DHT). These effects include increasing protein synthesis, promoting bone formation, lowering cholesterol levels, stimulating the production of red blood cells, and decreasing fat deposition.
一般的な説明
Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. Mesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH. Experiments of mesterolone serving as a potential treatment of depression are still undergoing.

メステロロン上流と下流の製品情報

メステロロン生産企業

メステロロンスペクトルデータ(IR1、MS)

1424-00-6, メステロロンキーワード

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メステロロン

危険有害性情報のコード(GHS)

メステロロン 価格

MSDS Information

メステロロン 化学特性,用途語,生産方法

メステロロン 上流と下流の製品情報

メステロロン 生産企業

メステロロン スペクトルデータ(IR1、MS)

1424-00-6, メステロロン キーワード

メステロロン価格

メステロロン化学特性,用途語,生産方法

メステロロン上流と下流の製品情報

メステロロン生産企業

メステロロンスペクトルデータ(IR1、MS)

1424-00-6, メステロロンキーワード