ピランテルパモ酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

ピランテルパモ酸塩 価格

MSDS Information

• Pyrantel pamoate

ピランテルパモ酸塩 化学特性,用途語,生産方法

• 外観

  うすい黄色～黄色, 結晶性粉末～粉末

• 溶解性

  ジメチルホルムアミドにやや溶けにくい。メタノール、及びエタノールに極めて溶けにくい。水、酢酸エチル、エーテル及びクロロホルムにほとんど溶けない。エタノール(95)に極めて溶けにくく、水にほとんど溶けない。

• 用途

  動物用医薬品定量用の標準品。

• 効能

  駆虫薬

• 商品名

  コンバントリン (佐藤製薬); コンバントリン (佐藤製薬)

• 化学的特性

  Pale yellow or yellow powder.

• 使用

  An antiparasitic agent used in the treatment of intestinal parasites such as hookworms and roundworms (Ascaris lumbricoides, aka ascarids in humans) in domesticated animals such as horses, cattle, sheep, pigs, cats, dogs, and many other species.

• 適応症

  Pyrantel pamoate (Antiminth) is a agonist at the nicotinic acetylcholine receptor, and its actions result in depolarization and spastic paralysis of the helminth muscle. Its selective toxicity occurs primarily because the neuromuscular junction of helminth muscle is more sensitive to the drug than is mammalian muscle. This drug is administered orally, and because very little is absorbed, high levels are achieved in the intestinal tract. Less than 15% of the drug and its metabolites are excreted in urine.

• 一般的な説明

  Odorless light yellow to tan crystalline powder. Tasteless. Used medicinally against nematodes in animals.

• 空気と水の反応

  May be sensitive to prolonged exposure to air and light . Insoluble in water.

• 反応プロフィール

  Pyrantel pamoate may react with acids to liberate heat. May react exothermically enough with strong oxidizing acids to ignite the reaction products. Heat is also generated with caustic solutions. Generates flammable or toxic gases with alkali metals and hydrides and other reducing agents.

• 火災危険

  Flash point data for Pyrantel pamoate are not available; however, Pyrantel pamoate is probably combustible.

• 臨床応用

  Trans-1,4,5,6,-Tetrahydro-1-methyl-2-[2-(2 -thienyl)ethenyl]pyrimidine pamoate (Antiminth) is a depolarizing neuromuscularblocking agent that causes spastic paralysis insusceptible helminths. It is used in the treatment of infestationscaused by pinworms and roundworms (ascariasis).Because its action opposes that of piperazine, the twoanthelmintics should not be used together. More than halfof the oral dose is excreted in the feces unchanged.Adverse effects associated with its use are primarilygastrointestinal.

• 副作用

  Pyrantel pamoate is active against several roundworms: A. lumbricoides, Ancylostoma duodenale, Necator americanus, and E. vermicularis. Pyrantel is an alternative drug of choice in treating infections with A. lumbricoides, E. vermicularis (pinworms), and hookworms (N. americanus and A. duodenale). It is not recommended for pregnant patients or for children under age 1 year.
  Although most of the drug remains in the intestinal lumen, enough can be absorbed systemically to cause headache, dizziness, and drowsiness. No major adverse effects have been reported on renal, hepatic, or hematological systems.

ピランテルパモ酸塩 生産企業

Global(453)Suppliers

ピランテルパモ酸塩 スペクトルデータ(MS)

22204-24-6, ピランテルパモ酸塩 キーワード