モノクローナル抗チューブリン, C末端チロシン抗体 マウス宿主抗体

モノクローナル抗チューブリン, C末端チロシン抗体 マウス宿主抗体 化学特性,用途語,生産方法

• 使用

  Monoclonal Anti-Tyrosine Tubulin has been used in:
  
  • indirect immunofluorescent labelling
  • immunoblotting technique
  • immunocytochemical staining
  
  

• 一般的な説明

  Monoclonal Anti-Tyrosine Tubulin (mouse IgG3 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Tubulin as a cylindrical filamentous structure and is present in almost all eukaryotic cells. Tubulin is a heterodimer which consists of α-tubulin and β-tubulin; both subunits have a molecular weight of 55 kDa and share considerable homology.

• Biochem/physiol Actions

  Tubulin acts as a major building block of microtubules. Tubulin tyrosinylation is involved in the assembly status of tubulin. A specific tubulinyl tyrosine carboxypeptidase removes the terminal tyrosine to yield an α-tubulin terminating in a glutamic acid residue while another enzyme modifies the α-tubulin by addition of tyrosine to the carboxy terminus to offer a potential cycle of tyrosine addition and loss.

モノクローナル抗チューブリン, C末端チロシン抗体 マウス宿主抗体 生産企業

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