4-(2-ヒドロキシエチル)-1-ピペラジンプロパンスルホン酸

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H315：皮膚刺激

  H319：強い眼刺激

  H332：吸入すると有害

  H335：呼吸器への刺激のおそれ

• 注意書き

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P310：ただちに医師に連絡すること。

4-(2-ヒドロキシエチル)-1-ピペラジンプロパンスルホン酸 価格

MSDS Information

• 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid

4-(2-ヒドロキシエチル)-1-ピペラジンプロパンスルホン酸 化学特性,用途語,生産方法

• 外観

  白色結晶性粉末

• 溶解性

  水によく溶ける(2.5g/10ml水)。0℃において2.5mol/lで飽和する。

• 化学的特性

  white crystalline powder

• 使用

  HEPPS (EPPS) is a commonly used Good's buffer. It is often used as separator in ultrathin isoelectric focusing gels and enhances the resolution of phosphoglucomutase. It is used as a buffering agent in biology and biochemistry. HEPPS is a biological buffer with a useful pH range of 7.3-8.7 and a pKa=8.0 at 25°C. Research on mice with Alzheimer's disease-like amyloid beta plaques has shown that HEPPS can cause the plaques to break up, reversing some of the symptoms in the mice. HEPPS was reported to dissociate amyloid beta oligomers in patients' plasma samples enabling blood diagnosis of Alzheimer's disease.

• 一般的な説明

  HEPPS, or N-(2-Hydroxyethyl)piperazine-N′-(3-propanesulfonic acid), is a zwitterionic buffering agent commonly used in biochemical and molecular biology research. Its mechanism of action is rooted in its ability to maintain a stable pH environment, which is crucial for various enzymatic reactions and protein studies. HEPPS is especially favoured for its buffering capacity in the physiological pH range, typically between pH 6.8 and 8.2, making it ideal for biological assays and cell culture experiments. This compound is extensively utilized in preparing cell culture media, where maintaining a consistent pH is essential for cell viability and growth. Additionally, HEPPS is employed in biochemical assays, such as enzyme kinetics studies, where precise pH control is necessary to accurately measure enzymatic activity. Furthermore, HEPPS has found applications in molecular biology techniques, including nucleic acid purification, PCR (polymerase chain reaction), and protein analysis by SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis). Its compatibility with various biological systems and stability under physiological conditions make HEPPS a valuable tool in research laboratories for maintaining optimal pH conditions and ensuring reliable experimental outcomes in various biochemical and molecular biology studies.

4-(2-ヒドロキシエチル)-1-ピペラジンプロパンスルホン酸 生産企業

Global(358)Suppliers

4-(2-ヒドロキシエチル)-1-ピペラジンプロパンスルホン酸 スペクトルデータ(¹HNMR、IR1、IR2、MS、Raman)

16052-06-5, 4-(2-ヒドロキシエチル)-1-ピペラジンプロパンスルホン酸 キーワード