Elderberry is the dark purple berry of the European or black elder tree, which grows in the warmer parts of Europe, North America, Asia, and Northern Africa. Elderberry has been used in folk medicine to treat colds and flu. Several investigations have demonstrated the anti-inflammatory, antiviral, antiproliferative, anti-diabetic, and immunostimulatory effects of elderberries Elderberry extract (EB) is known to contain high levels of anthocyanins which could exert vascular protective effects. The majority of elderberry extracts are derived from fruit, although in a few cases the extracts are derived from flowers. Elderberry extract has also demonstrated beneficial effects related to cardiovascular diseases (CVDs), cancer [23], and diabetes, as well as having anti-inflammatory properties [24] and immune-stimulating, anti-depressive, chemo-preventive, and atheroprotective effects[1-3].