モノクローナル抗D1ドーパミンレセプター抗体 ラット宿主抗体

モノクローナル抗D1ドーパミンレセプター抗体 ラット宿主抗体 価格

モノクローナル抗D1ドーパミンレセプター抗体 ラット宿主抗体 化学特性,用途語,生産方法

• 使用

  Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
  Immunofluorescence (1 paper)
  Immunohistochemistry (1 paper)

• 一般的な説明

  Monoclonal Anti-D1 Dopamine Receptor (rat IgG2a isotype) is derived from the rat hybridoma 1-1-F11 S.E6 produced by the fusion of mouse myeloma cells and splenocytes from rat immunized with recombinant fusion protein containing the C-terminal 97 amino acid of human D1 dopamine receptor. Dopamine receptors belong to the family of seven transmembrane domain G protein coupled receptors (GPCRs). Dopamine receptors are mainly localized in the striatum, limbic system, the brain cortex and the infundibulum. The D1-like family consists of the D1 and D5 receptors.

• Biochem/physiol Actions

  D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. D1 receptors are expressed on airway smooth muscle (ASM) and regulate smooth muscle force via cAMP activation of protein kinase A. It is a potential target for therapeutic relaxation of ASM.

モノクローナル抗D1ドーパミンレセプター抗体 ラット宿主抗体 生産企業

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