4-アミノ安息香酸ブチル

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H315：皮膚刺激

  H317：アレルギー性皮膚反応を起こすおそれ

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

4-アミノ安息香酸ブチル 価格

MSDS Information

• Butyl 4-aminobenzoate

4-アミノ安息香酸ブチル 化学特性,用途語,生産方法

• 外観

  白色～わずかにうすい黄色, 結晶～粉末

• 溶解性

  エタノール、クロロホルム、エーテル、脂肪油に易溶。水に難溶。

• 用途

  有機合成原料、医薬品原料。

• 効能

  表面麻酔薬, カリウムチャネル遮断薬

• 化学的特性

  It is a solid at room temperature, with a melting point of 58°C and a boiling point of 173.4°C (at 8mmHg). Butyl p-aminobenzoate is insoluble in water.

• 使用

  n-Butyl 4-aminobenzoate is used as pharmaceutical intermediate.

• 調製方法

  Butyl p-aminobenzoate is manufactured via esterification of p-nitrobenzoic acid with n-butyl alcohol, followed by the reduction of the nitro group to an amino group.

• 定義

  ChEBI: An amino acid ester resulting from the formal condensation of the carboxy group of 4-aminobenzoic acid with the hydroxy group of butan-1-ol. Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for r lief of pain and itching associated with some anorectal disorders.

• 一般的な説明

  Yellow powder. Insoluble in water.

• 空気と水の反応

  May be sensitive to light and air. Insoluble in water. Slowly hydrolyzed when boiled in water. Also will hydrolyze under high and low pH conditions .

• 反応プロフィール

  Butyl 4-aminobenzoate is an aminophenyl ester derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

• 火災危険

  Flash point data for Butyl 4-aminobenzoate are not available. Butyl 4-aminobenzoate is probably combustible.

• 純化方法

  Crystallise Butamben from EtOH. [Beilstein 14 IV 1130.]

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4-アミノ安息香酸ブチル 生産企業

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