N-アセチルシステインアミド

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P501：内容物/容器を．．．に廃棄すること。

N-アセチルシステインアミド 価格

N-アセチルシステインアミド 化学特性,用途語,生産方法

• 使用

  N-acetylcysteine amide has been used:
  
  • to protect retinal pigment epithelium (RPE) from oxidative stress
  • to show that increased expression of cell adhesion molecule 4 (CADM4) in oligodendrocytes inhibits myelination
  • to protect cells from apoptosis induced by shikonin plus erlotinib/gefitinib
  • as a component in various culture media
  
  

• Biochem/physiol Actions

  N-acetylcysteine amide is a membrane penetrating antioxidant with antiinflamatory activity through regulation of activation of NF-κB and HIF-1α as well as modulation of ROS. The compound readily crosses cell membranes, replenishes intracellular GSH, and defends the cell from oxidative stress. In contrast to DTT, AD4 is able to directly reduce intracellularl GSSG to GSH without the involvement of glutathione peroxidase. Such direct thiol exchange might have a protective effect. This compound has a potential in research and exploration for treatment of neurodegeneration, radiation exposure, and other oxidation-mediated disorders.

• 臨床応用

  N-Acetylcysteine amide has antioxidant and is often used in the preparation of Eyedrops. It has been used as a treatment for the prevention or healing of cataracts, macular degeneration, and other degenerative eye disorders.

N-アセチルシステインアミド 上流と下流の製品情報

N-アセチルシステインアミド 生産企業

Global(96)Suppliers

38520-57-9, N-アセチルシステインアミド キーワード