Nα-(9H-フルオレン-9-イルメトキシカルボニル)-L-ヒスチジン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

Nα-(9H-フルオレン-9-イルメトキシカルボニル)-L-ヒスチジン 価格

Nα-(9H-フルオレン-9-イルメトキシカルボニル)-L-ヒスチジン 化学特性,用途語,生産方法

• 説明

  Nα-Fmoc-L-histidine (FMOC-HIS-OH) holds great significance as a synthetic amino acid extensively employed in peptide synthesis. Its versatility makes it a highly sought-after reagent, widely used in various synthetic processes to create peptides, proteins, and even small molecules. Moreover, it catalyzes peptide and protein synthesis, further enhancing its utility. It is pivotal in unravelling biological processes such as enzymatic catalysis, protein structure, and drug design. Notably, this remarkable amino acid aids in understanding cell signalling pathways, which bear paramount importance in comprehending the mechanisms underlying diseases. The mechanism of action for Nα-Fmoc-L-histidine revolves around its ability to form essential peptide bonds. These bonds arise through a reaction with specific reagents, like DCC, leading to the creation of peptides. Subsequently, deprotection of the peptide bond occurs with the addition of a base, such as sodium hydroxide, followed by an acid, like trifluoroacetic acid.

• 使用

  Nα-Fmoc-L-histidine is an N-Fmoc-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.

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