シスタミン二塩酸塩

化学名:シスタミン二塩酸塩

CAS番号.56-17-7

英語名:Cystamine dihydrochloride

CBNumberCB8485955

MFC4H14Cl2N2S2

MW225.2

别名

シスタミン二塩酸塩

二塩酸シスタミン

2,2'-ジチオビス(エタンアミン)·二塩酸塩

シスタミン二塩酸塩物理性質

融点	217-220 °C (dec.)(lit.)
貯蔵温度	Store below +30°C.
溶解性	H2O: 可溶性、1.0g/10 mL、透明からほぼ透明、無色からほぼ無色 (<5.5 NTU)
外見	結晶性粉末、結晶またはチャンク
色	白から黄色
由来生物	synthetic
水溶解度	溶ける
Sensitive	Hygroscopic
Merck	14,2776
BRN	3616850
安定性：	安定。強力な酸化剤とは相容れない。
InChI	InChI=1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H
InChIKey	YUFRRMZSSPQMOS-UHFFFAOYSA-N
SMILES	S(CCN)SCCN.Cl.Cl
CAS データベース	56-17-7(CAS DataBase Reference)
EPAの化学物質情報	Ethanamine, 2,2'-dithiobis-, dihydrochloride (56-17-7)

安全性情報

危険有害性情報のコード(GHS)

外観
白色～ほとんど白色粉末～結晶
溶解性
水に溶け、エタノール及びアセトンにほとんど溶けない。
用途
有機合成用試薬。
化学的特性
white powder
使用
Cystamine dihydrochloride acts as an anti-infective agent, which is used in the treatment of urinary tract infections. It is also used as a radiation-protective agent that interferes with sulfhydryl enzymes. Further, it serves as a heparin antagonist and sulfhydryl modifying reagent. In addition to this, it is used as an inhibitor of TGase.
安全性プロファイル
A poison by subcutaneous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl, SOx, and NOx. See also SULFIDES.
純化方法
Recrystallise the salt by dissolving in EtOH containing a few drops of dry EtOH/HCl, filtering and adding dry Et2O. The solid is dried in a vacuum and stored in a dry and dark atmosphere. It has been recrystallised from EtOH (solubility: 1g in 60mL of boiling EtOH) or MeOH (plates). The free base has b 90-Purification of Biochemicals — Amino Acids and Peptides 100o/0.001mm, 106-108o/5mm and 135-136o/760mm, d 4 1.1559, n D 1.5720. [Verly & Koch Biochem J 58 663 1954, Gonick et al. J Am Chem Soc 76 4671 1954, Jackson & Block J Biol Chem 113 137 1936.] The dihydrobromide has m 238-239o (from EtOH/Et2O) [Viscontini Helv Chim Acta 36 835 1953]. [Beilstein 4 H 287, 4 IV 1578.]

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