成長ホルモン放出ペプチド

化学名:成長ホルモン放出ペプチド

CAS番号.87616-84-0

英語名:Growth hormone releasing peptide

CBNumberCB8421540

MFC46H56N12O6

MW873.01

MOL File87616-84-0.mol

别名

成長ホルモン放出ペプチド【合成】

成長ホルモン放出ヘキサペプチド

[D-TRP7, ALA8, D-PHE10]-Α-メラニン細胞刺激ホルモンアミドフラグメント 6-11

成長ホルモン放出ペプチド物理性質

融点	>160o C (Dec.)
沸点	1407.0±65.0 °C(Predicted)
比重(密度)	1.333±0.06 g/cm3(Predicted)
貯蔵温度	−20°C
溶解性	メタノール（微量）、水（微量）
外見	個体
酸解離定数(Pka)	13.42±0.46(Predicted)
色	ホワイトからオフホワイト
シーケンス	is-D-Trp-Ala-Trp-D-Phe-Lys-NH2\|H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
InChIKey	WZHKXNSOCOQYQX-FUAFALNISA-N
SMILES	C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](CC1N=CNC=1)N
CAS データベース	87616-84-0(CAS DataBase Reference)

安全性情報

WGK Germany

危険有害性情報のコード(GHS)

成長ホルモン放出ペプチド価格

製品番号	包装	価格	製品説明	購入
富士フイルム和光純薬株式会社(wako) W01BCS4008401	5mg	￥32000		購入
富士フイルム和光純薬株式会社(wako) W01BCS4008401	25mg	￥126000		購入
Sigma-Aldrich Japan M2910	5mg	￥37100	[D-Trp7, Ala8, D-Phe10]-α-メラニン細胞刺激ホルモンアミドフラグメント 6-11 ≥97% (HPLC)	購入
富士フイルム和光純薬株式会社(wako) W01LKTG2969	1mg	￥28400	成長ホルモン放出ヘキサペプチド	購入
富士フイルム和光純薬株式会社(wako) W01LKTG2969	2mg	￥48200	成長ホルモン放出ヘキサペプチド	購入

成長ホルモン放出ペプチド化学特性,用途語,生産方法

説明
Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. They have no structural homology with GHRH and act via specific receptors present either at the pituitary or the hypothalamic level both in animals and in humans.
使用
Growth hormone releasing peptide-6 can promote the secretion of growth hormone, regulate food intake, increase weight, and promote animal growth.
生物学の機能
Growth hormone releasing peptide (GHRH) is an endocrine hormone produced in the hypothalamus that acts on the receptors (GHRH-R) of the anterior pituitary gland to stimulate the release of growth hormone (GH). GHRH includes GHRH-2 and GHRH-6, which have slightly different functions. GHRH-2 is widely used to diagnose patients with growth hormone deficiency (GHD) and is believed to induce not only growth hormone (GH) release, but also adrenocorticotropic hormone (ACTH) release. GHRH-6 is part of a group of synthetic small peptides with potent growth hormone releasing activity, which has cellular and cardioprotective effects and can be used in heart disease treatment research.
作用機序
Growth hormone releasing peptide is generally accepted that GHRPs stimulate the release of GH by acting at the level of the pituitary through a receptor different to that for the endogenous GH-releasing hormone (GHRH). In addition, it has been reported that there are specific binding sites for these peptides in the hypothalamus and that systemic administration of GHRPs increases the expression of the immediate early gene c-fos in a subpopulation of hypothalamic neurons.
副作用
Carpal tunnel syndrome.Increased insulin resistance.
Type 2 diabetes.
Swelling in the arms and legs (edema)
Joint and muscle pain.
For men, enlargement of breast tissue (gynecomastia).
Increased risk of certain cancers.
Physiological effects
Growth hormone releasing peptide (GHRP) is a cyclase inhibitor that blocks the release of endogenous growth hormone.The peptide acts on both igf-i and somatotrophs, with receptor activity in the hypothalamus.GHRP can be used to increase body weight and control obesity.It has been shown to stimulate cell division and inhibit apoptosis in vitro.
Solubility in water
It is recommended to reconstitute the lyophilized growth hormone releasing peptide in sterile 18MΩ-cm H₂O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.

成長ホルモン放出ペプチド生産企業

87616-84-0, 成長ホルモン放出ペプチドキーワード

Send Inquriy

成長ホルモン放出ペプチド

危険有害性情報のコード(GHS)

成長ホルモン放出ペプチド 価格

成長ホルモン放出ペプチド 化学特性,用途語,生産方法

成長ホルモン放出ペプチド 生産企業

87616-84-0, 成長ホルモン放出ペプチド キーワード

成長ホルモン放出ペプチド価格

成長ホルモン放出ペプチド化学特性,用途語,生産方法

成長ホルモン放出ペプチド生産企業

87616-84-0, 成長ホルモン放出ペプチドキーワード