(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol 価格

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol 化学特性,用途語,生産方法

• 一般的な説明

  (R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity.

• Biochem/physiol Actions

  (R)-FTY720-OMe helps to block DNA synthesis and actin rearrangement induced by sphingosine 1-phosphate (S1P) in MCF-7 breast cancer cells. It can also reduce sphingosine kinase 2 (SK2) expression and prevent DNA synthesis in HEK 293 cells. (R)-FTY720-OMe has anti-breast cancer potential.

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol 生産企業

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