C-反応性タンパク, ヒト, 組換え体

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H290：金属腐食のおそれ

• 注意書き

  P234：他の容器に移し替えないこと。

  P390：物的被害を防止するためにも流出したものを吸収 すること。

C-反応性タンパク, ヒト, 組換え体 価格

C-反応性タンパク, ヒト, 組換え体 化学特性,用途語,生産方法

• 使用

  For immunological applications in the preparation of antisera

• 一般的な説明

  Recombinant, human C-reactive protein expressed in E. coli. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca²⁺-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.

• Biochem/physiol Actions

  C-reactive protein (CRP) plays a key role in the complement pathway, apoptosis, phagocytosis, nitric oxide (NO) release, and the production of interleukin-6 and tumor necrosis factor-α. It participates in the uptake of low-density lipoprotein in macrophages. CRP levels are elevated in people suffering from appendicitis, cholecystitis, pancreatitis, and meningitis. It plays a vital role in the pathophysiology of cardiovascular disease. Hence it is used as a marker of infection and cardiovascular events.

C-反応性タンパク, ヒト, 組換え体 生産企業

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