N-ニトロソジメチルアミン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H301：飲み込むと有毒

  H330：吸入すると生命に危険

  H350：発がんのおそれ

  H372：長期にわたる、または反復暴露により臓器の障 害

  H411：長期的影響により水生生物に毒性

• 注意書き

  P260：粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P271：屋外または換気の良い場所でのみ使用すること。

  P284：呼吸用保護具を着用すること。

  P301+P310：飲み込んだ場合：直ちに医師に連絡すること。

  P304+P340：吸入した場合：空気の新鮮な場所に移し、呼吸しやすい 姿勢で休息させること。

  P310：ただちに医師に連絡すること。

  P314：気分が悪い時は、医師の診断/手当てを受けること。

  P320：特別な治療が緊急に必要である（このラベ ルの．．．を見よ）。

  P321：特別な処置が必要である（このラベルの．．． を見よ）。

  P330：口をすすぐこと。

  P403+P233：換気の良い場所で保管すること。容器を密閉 しておくこと。

  P405：施錠して保管すること。

  P501：内容物/容器を．．．に廃棄すること。

N-ニトロソジメチルアミン 価格

N-ニトロソジメチルアミン 化学特性,用途語,生産方法

• 外観

  うすい黄色〜黄色, 澄明の液体

• 溶解性

  水, アルコール, アセトンに易溶。水、エタノール及びアセトンに極めて溶けやすい。水、エタノール及びアセトンに極めて溶けやすい。

• 用途

  潤滑油添加剤 安定剤、酸化?老化防止剤、各種添加物等その他、柔軟剤

• 使用上の注意

  不活性ガス封入

• 化学的特性

  N-Nitrosodimethylamine is a yellow oily liquid. Faint, characteristic odor.

• 物理的性質

  Yellow, oily liquid with a faint, characteristic odor

• 使用

  N-Nitrosodimethylamine is a highly toxic semi-volatile organic compound and a suspected human carcinogen. It induces liver tumors in rats after chronic exposure to low doses (1,2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.NDMA and NDEA were found as an impurity in generic versions of valsartan, losartan and irbesartan.

• 調製方法

  Dimethylnitrosamine (DMN) is prepared by the addition of acetic acid and sodium nitrite to dimethylamine. It came into industrial prominence in the manufacture of 1,1- dimethylhydrazine, a rocket fuel component, probably in the 1940s in Germany and in the mid-1950s in the United States. DMN is no longer used except for research. OSHA identified DMN as a carcinogen in 1974. In 1976, the last plant to make DMN was closed. DMN was first considered by IARC in 1971. The current IARC classification of DMN is 2A: “The agent is probably carcinogenic to humans, based upon positive cancer findings in animal studies.” For this reason, DMN is discussed here as an example of one of a large group of nitrosamines generally regarded as carcinogenic. IARC Monographs 1 and 17 and other publications discuss the toxicology, biochemistry, environmental impact, and carcinogenicity of many nitrosamines.

• 一般的な説明

  Yellow oily liquid with a faint characteristic odor. Boiling point 151-153°C. Can reasonably be expected to be a carcinogen. Used as an antioxidant, as an additive for lubricants and as a softener of copolymers. An intermediate in 1,1-dimethylhydrazine production.

• 空気と水の反応

  Water soluble.

• 反応プロフィール

  N-NITROSODIMETHYLAMINE is sensitive to exposure to light, especially ultraviolet light. Is stable at room temperature for more than 14 days in aqueous solution at neutral and alkaline pH in the absence of light. Slightly less stable at strongly acid pH at room temperature. Incompatible with strong oxidizing agents. Also incompatible with strong bases. Can be reduced by reducing agents. Incompatible with hydrogen bromide in acetic acid. Also photo chemically reactive.

• 健康ハザード

  N-nitrosodimethylamine (DMN) is a liver toxin and is carcinogenic in many species of test animals.

• 火災危険

  When heated to decomposition, N-NITROSODIMETHYLAMINE emits toxic fumes of nitrogen oxides. Avoid exposure to ultraviolet light.

• 職業ばく露

  Nitrosodimethylamine was formerly used in the production of rocket fuels. Presently used as an antioxidant; as an additive for lubricants and as a softener of copolymers. It is used as an intermediate for 1,1-dimethylhydrazine.

• 発がん性

  N-Nitrosodimethylamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

• 輸送方法

  UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. PG I.

• 純化方法

  Dry the nitrosamine over anhydrous K2CO3 or dissolve it in Et2O, dry it over solid KOH, filter, evaporate Et2O and distil the yellow oily residue through a 30cm fractionating column discarding the first fraction which may contain Me2N. Also dry over CaCl2 and distil it at atmospheric pressure. All operations should be done in an efficient fume cupboard as the vapors are TOXIC and CARCINOGENIC. [Fischer Chem Ber 8 1588 1875, Romberg Recl Trav Chim, Pays-Bas 5 248 1886, Hatt Org Synth Coll Vol II 211 1961, Krebs & Mandt Chem Ber 108 1130 1975.] 2,6-Dimethyl-2,4,6-octatriene see neo-alloocimene below.

• 不和合性

  Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong acids, especially peracids strong bases. Sensitive to UV light. Should be stored in dark bottles.

• 廃棄物の処理

  Pour over soda ash, neutralize with HCl, then flush to drain with large volumes of water. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

N-ニトロソジメチルアミン 上流と下流の製品情報

N-ニトロソジメチルアミン スペクトルデータ(¹HNMR、¹³CNMR、ESR、IR1、IR2、MS)

62-75-9, N-ニトロソジメチルアミン キーワード