プロテインジスルフィドイソメラーゼ ウシ肝臓由来

プロテインジスルフィドイソメラーゼ ウシ肝臓由来 価格

プロテインジスルフィドイソメラーゼ ウシ肝臓由来 化学特性,用途語,生産方法

• 使用

  Protein Disulfide Isomerase from bovine liver has been used:
  
  • to study the functional role of PDI in parasite infection and the interaction between macrophage PDI and?L. chagasi
  • in the in vitro translation reaction for the generation of disulfide bonds
  • in insulin-disulfide reduction assay and peptide binding assay
  • as a positive control in thiol-disulfide oxidoreductase activity assay
  
  

• 一般的な説明

  Protein disulfide isomerase (PDI) from bovine liver is a homodimer with a molecular weight of 107 kDa with the monomer corresponding to 57 kDa. The isoelectric point (pI) is approximately 4.2. The enzyme is a glycoprotein with 12% total carbohydrate content comprising of mannose, galactose, N-acetyl neuraminic acid (NANA) and 2-acetamido-2-deoxyglucose. PDI is an ubiquitous redox chaperone enzyme. It belongs to the, thioredoxin superfamily and is high conserved.

• Biochem/physiol Actions

  Protein Disulfide Isomerase (PDI) is mainly located in the endoplasmic reticulum (ER), where it assists in protein-folding and thiol-disulfide exchanges. It aids protein refolding in vitro allowing recombinant proteins to achieve their native state.

プロテインジスルフィドイソメラーゼ ウシ肝臓由来 生産企業

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