(5α,12β,19α)-2,3-ジデヒドロ-1-メチルアスピドスペルミジン-3-カルボン酸メチル

(5α,12β,19α)-2,3-ジデヒドロ-1-メチルアスピドスペルミジン-3-カルボン酸メチル 化学特性,用途語,生産方法

• 説明

  A further alkaloid isolated from Vinca minor L., this base is possibly optically inactive, the specific rotation reported being [α]_D 00 ± 2° (c 1.0, EtOH). The ultraviolet spectrum in EtOH has a broad absorption maximum at 338 mil and an inflexion at 310 mil. The structure has been confirmed by the synthesis of the (±)-form.

• 参考文献

  Kokry, Dubravkova, Sefecovic.,Experientia, 18,564 (1962)
  Mokryetal., ibid, 19,311 (1963)
  Zachystalova, Strouf, Trojanek., Chern. & Ind., 610 (1963)
  Synthesis: Kutney et al., J. Amer. Chern. Soc., 90,3891 (1968)