(13S)-8α,13-ジヒドロキシセラチナン-5-オン

(13S)-8α,13-ジヒドロキシセラチナン-5-オン 化学特性,用途語,生産方法

• 解説

  C16H25NO3(279.37)．ヒカゲノカズラ科トウゲシバLycopodium serratumに見いだされるリコポジウムアルカロイドの一つ．融点244～245 ℃．[α]_D－28°(エタノール)．[CAS 5545-99-3]"
  森北出版「化学辞典（第2版）

• 説明

  A further alkaloid present in Lycopodium serratum Thunb. vaT. thunbergii Mak. The base crystallizes from Me₂CO in colourless prisms and has [α]⁸_D - 27.8° (c 1.44, EtOH). Two non-phenolic hydroxyl groups are present and the alkaloid forms the 8-0-acetate, m.p. 244-5°C; the l3-0-acetate, m.p. 240-2°C and the di-O-acetate, m.p. 1 57-8°C. The tetracyc1ic structure has been proposed on the basis of the mass spectra of the alkaloid and a tentative biogenesis from lycodoline-type alkaloids also proposed.

• 参考文献

  Inubushi et al., Tetrahedron Lett., 1537 (1966)
  Mass spectra:
  Inubishietal., Tetrahedron, 24,3541 (1968)
  Stereochemistry :
  Inubushi et al., Tetrahedron Lett., 1551 (1966)
  Biosythesis:
  Inubushi et aI., Chem. Pharm. Bull. (Tokyo), 16,92 (1968)

(13S)-8α,13-ジヒドロキシセラチナン-5-オン 生産企業

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