(12α)-3,18-ジヒドロ-17-メチルリコジン-1(2H)-オン

(12α)-3,18-ジヒドロ-17-メチルリコジン-1(2H)-オン 化学特性,用途語,生産方法

• 説明

  One of the numerous alkaloids obtained from the Lycopodium species, this base occurs in L. sausaurus and gives colourless crystals from Me₂CO. It is laevorotatory having [α]²⁰_D - 71.8° (c 0.792, EtOH). The ultraviolet spectrum consists of a single absorption maximum at 257 mJ.l.. The alkaloid may be characterized as the methiodide which forms colourless needles from aqueous Me₂CO, m.p. 258°C. When heated with Pd-C in a stream of nitrogen at 290-300°C it yields 7-methylquinoline and 6-methyl-a-pyridone. From the above structure it will be seen that the alkaloid is a stereoisomer of a-Obscurine (q.v.).

• 参考文献

  Deulofeu, DeLanghe.,J. A mer. Chern. Soc., 64, 968 (1942)
  Structure:
  Ayer et aZ., Tetrahedron, 21,2168 (1965)