キシラジン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H301：飲み込むと有毒

キシラジン 価格

MSDS Information

• N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine

キシラジン 化学特性,用途語,生産方法

• 効能

  鎮痛薬 (獣医薬), α2アドレナリン受容体作動薬

• 説明

  Xylazine is an agonist of α₂-adrenergic receptors (K_i = 194 nM). It is an analog of clonidine, an α₂-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard .

• 使用

  Xylazine is an α2 class of adrenergic receptor agonist. Xylazine is a clonidine analoque that acts on presynaptic and postsynaptic receptors as an a 2-adrenergic agonist.

• 一般的な説明

  Xylazine is soluble in methanol (50 mg/ml), yielding a clear, colorless solution. It is also soluble in dilute HCl acid and in chloroform. Xylazine is practically insoluble in water and in alkali solutions.

• 作用機序

  Xylazine is marketed as its hydrochloride salt as Rompun (100 mg/mL) and Anased (20 mg/mL) injectable solutions for intravenous administration to horses and dogs, respectively. The actions of xylazine may be reversed by the administration of yohimbine, an indolalkylamine alkaloid, that blocks those α2- adrenoreceptors that are stimulated by xylazine.

• 副作用

  High doses of Xylazine can cause dizziness, vomiting, high blood sugar, blurry vision and even overdose deaths. If you inject xylazine into your body, you also may develop skin ulcers and severe wounds that can spread and worsen quickly. Xylazine can lead to depression of the central nervous system along with other adverse effects. As for animals, they may show profound salivation following an injection with xylazine. Other adverse effects for dogs and cats include: muscle tremors, bradycardia with AV-block, hypotension, reduced respiratory rate, movement in response to strong auditory stimuli, and increased urination in cats.
  

• 安全性プロファイル

  Poison by ingestion, subcutaneous, and intravenous routes. Human systemic effects: change in motor activity, fall in blood pressure, miosis, pleural thickening, pulse rate decrease, somnolence. When heated to decomposition it emits very toxic fumes of NOx and SOx.

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キシラジン 生産企業

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キシラジン スペクトルデータ(¹HNMR)

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