4,4'-ジイソシアン酸メチレンジフェニル

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H315：皮膚刺激

  H317：アレルギー性皮膚反応を起こすおそれ

  H319：強い眼刺激

  H332：吸入すると有害

  H334：吸入するとアレルギー、喘息または、呼吸困難 を起こすおそれ

  H335：呼吸器への刺激のおそれ

  H351：発がんのおそれの疑い

  H373：長期にわたる、または反復暴露により臓器の障 害のおそれ

• 注意書き

  P202：全ての安全注意を読み理解するまで取り扱わないこ と。

  P260：粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P308+P313：暴露または暴露の懸念がある場合：医師の診断/手当てを 受けること。

4,4'-ジイソシアン酸メチレンジフェニル 価格

MSDS Information

• 1,1'-Methylenebis(4-isocyanatobenzene)

4,4'-ジイソシアン酸メチレンジフェニル 化学特性,用途語,生産方法

• 外観

  白色～ほとんど白色粉末～塊

• 溶解性

  水に不溶。ベンゼン, トルエンに可溶。

• 用途

  有機合成原料。

• 用途

  スパンデックス繊維?合成皮革,ウレタンエラストマー?接着剤?塗料の原料、SRI:CHEMICAL ECONOMICS HANDBOOK;接着剤,塗料,スパンデックス繊維,合成皮革,ウレタンエラストマーなどの原料、化学工業日報社

• 主な用途／役割

  ポリウレタン樹脂、ポリウレタンプレポリマー等の原料、水性高分子イソシアネート系接着剤の架橋剤として使用される。

• 説明

  4,4'-Diphenylmethane-diisocyanate (MDI) is used in the manufacture of various polyurethane products - elastic and rigid foams, paints, lacquers, adhesives, binding agents, synthetics rubbers, and elastomeric fibers.

• 化学的特性

  white to light yellow flakes or crystals

• 使用

  Diphenyl methane diisocyanate (MDI) is widely used in polyurethane coatings, this product is made of polyurethane foam used as a warm (cold), building materials, vehicle, ship parts; masterwork can made car Block, buffer, synthetic leather, non plastic polyurethane, polyurethane elastic fiber, no plastic elastic fibers, films, adhesives.

• 定義

  ChEBI: A diisocyanate consisting of diphenylmethane with two isocyanate groups at the 4- and 4'-positions.

• 製造方法

  Phosgene (800 g, 8 mol) (for a safe source) was dissolved in o-dichlorobenzene (2000 mL), and the resulting solution was cooled in an ice-salt bath. To the stirred solution, a hot solution of 4,4'-diaminodiphenylmethane (200 g, 1.01 mol) in o-dichlorobenzene (1000 mL) was slowly added through a heated dropping funnel. The rate of addition was regulated so that the temperature of the phosgene solution did not rise substantially above 0°C. The fine suspension that resulted was slowly heated and additional phosgene (700 g, 7.1 mol) was added at 130 °C until a clear solution appeared. After purging with carbon dioxide, the solvent was removed in vacuo and the product was purified by vacuum distillation. At 156–158 °C (0.1 mmHg), 215 g (0.85 mol, 84%) of 4,4’-diphenylmethane diisocyanate was obtained. Several procedures for the preparation of isocyanates with phosgene have been described. Nevertheless, many of them require the delivery of gaseous phosgene from an external source, such as a pressurized cylinder.

• 一般的な説明

  Diphenylmethane-4,4-diisocyanate is a light yellow colored solid. 4,4'-Diphenylmethane diisocyanate is not soluble in water. 4,4'-Diphenylmethane diisocyanate may be toxic by ingestion, inhalation, or skin absorption. If in a solution 4,4'-Diphenylmethane diisocyanate may or may not burn depending on the nature of the material and/or the solvent. It's used to make plastics.

• 空気と水の反応

  4,4'-Diphenylmethane diisocyanate is not soluble in water.

• 反応プロフィール

  Isocyanates and thioisocyanates, such as 4,4'-Diphenylmethane diisocyanate, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].

• 健康ハザード

  Breathlessness, chest discomfort, and reduced pulmonary function.

• 火災危険

  Noncombustible; flash point (open cup) 202°C (395°F). MDI reactions with strong oxidizers, acids, and bases can be vigorous.

• 化学性质

  白色から微黄色の固体，ベンゼン，トルエン，アセトンなどに可溶

• 接触アレルゲン

  MDI is used in the manufacture of various polyurethane products: elastic and rigid foams, paints, lacquers, adhesives, binding agents, synthetic rubbers, and elastomeric fibers.

• 安全性プロファイル

  Poison by inhalation. Mildly toxic by ingestion. Human systemic effects by inhalation: increased immune response and body temperature. A skin and eye irritant. An allergic sensitizer. Questionable carcinogen. Mutation data reported. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx and SOx.

• 職業ばく露

  MDI is used in the production of polyurethane foams and plastics; polyurethane coatings; elastomers, and thermoplastic resins.

• 環境運命予測

  Due to its low vapor pressure (0.000 62 Pa at 20 ℃), MDI partitioning to the atmosphere is limited; and vapors are rapidly eliminated by reaction with hydroxyl radicals (22 h half-life). Degradation by either direct photolysis or hydrolysis by water vapor to methylenedianiline (MDA) does not play a significant role in the atmospheric fate of MDI. In water, the isocyanate group of MDI can be rapidly hydrolyzed to an amine (<1 min half-life) that in turn reacts at a much faster rate with another isocyanate group to yield urea. Because MDI has two isocyanate groups, these reactions lead to cross-linked polyureas, which are inert, insoluble solids. Unless MDI is well dispersed in water, these processes result in the formation of a solid polyurea crust that encases the unreacted material, restricts both water ingress and amine egress, and leads to higher yields of polyurea. Under stirred aqueous conditions, the fraction of 4,4'-MDI converted to 4,4'-MDA is less than 1%; unstirred, the fraction is 0.005%. MDI released to soil will not exhibit significant transport to other environmental media due to the favored reaction with water to form inert polyureas and binding to the soil biomass. As expected, pMDI and the waterinsoluble oligo- and polyureas that form when pMDI enters an aqueous environment showed no biodegradation over 28 days in a guideline study.

• 輸送方法

  UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required

• 合成方法

  アニリン塩酸塩にホルムアルデヒドを反応させて酸性縮合を行い，アルカリ中和後蒸留でメチレンジアニリン（MDA）を得る．このMDAを適当な溶媒に溶解し，ホスゲンを反応させて粗MDIを得る．副生物として重合体が生成するため，薄膜蒸留などにより精製する

• 不和合性

  May form explosive mixture with air. Isocyanates are highly flammable and reactive with many compounds, even with themselves. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Reaction with moist air, water or alcohols may form amines and insoluble polyureas and react exothermically, releasing toxic, corrosive or flammable gases, including carbon dioxide; and, at the same time, may generate a violent release of heat increasing the concentration of fumes in the air. Incompatible with amines, aldehydes, alkali metals, ammonia, carboxylic acids, caprolactum, alkaline materials, glycols, ketones, mercaptans, hydrides, organotin catalysts, phenols, strong acids, strong bases, strong reducing agents such as hydrides, urethanes, ureas. Elevated temperatures or contact with acids, bases, tertiary amines, and acylchlorides may cause explosive polymerization. Attacks some plastics, rubber and coatings. May accumulate static electrical charges, and may cause ignition of its vapors. Unstable above 100F/38C. Polymerizes at temperatures above 204C. Contact with metals may evolve flammable hydrogen gas.

• 廃棄物の処理

  Controlled incineration (oxides of nitrogen are removed from the effluent gas by scrubbers and/or thermal devices).

4,4'-ジイソシアン酸メチレンジフェニル 上流と下流の製品情報

4,4'-ジイソシアン酸メチレンジフェニル 生産企業

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4,4'-ジイソシアン酸メチレンジフェニル スペクトルデータ(¹HNMR、¹³CNMR、IR1、IR2、MS)

101-68-8, 4,4'-ジイソシアン酸メチレンジフェニル キーワード