塩酸バンコマイシン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H317：アレルギー性皮膚反応を起こすおそれ

  H334：吸入するとアレルギー、喘息または、呼吸困難 を起こすおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P284：呼吸用保護具を着用すること。

  P304+P340：吸入した場合：空気の新鮮な場所に移し、呼吸しやすい 姿勢で休息させること。

  P342+P311：呼吸に関する症状が出た場合：医師に連絡すること。

塩酸バンコマイシン 価格

MSDS Information

• Vancomycin hydrochloride

塩酸バンコマイシン 化学特性,用途語,生産方法

• 外観

  白色～うすい褐色, 結晶～粉末

• 溶解性

  水に溶けやすく、エタノールに極めて溶けにくく、エーテルにほとんど溶けない。

• 用途

  薬理研究用試薬。

• 用途

  グリコペプチド系抗生物質で す。細胞壁合成阻害作用を示します。グラム 陽性菌に対し、強い抗菌力を示します。

• 効能

  抗生物質, 細胞壁合成阻害薬

• 商品名

  バンコマイシン (東亜薬品); 塩酸バンコマイシン (塩野義製薬); 塩酸バンコマイシン (塩野義製薬)

• 説明

  Vancomycin is a glycopeptide antibiotic identified for its utility in the treatment of gram-positive bacteria, including penicillin-resistant staphylococci. It acts by binding to bacterial cell wall protein precursors, interfering with continuing protein synthesis. Vancomycin resistance in staphylococcal species has recently emerged as a clinical issue.

• 化学的特性

  off white powder

• 使用

  Vancomycin hydrochloride is the salt of a glycopeptide antibiotic isolated from Amycolatopsis orientalis in 1956. Vancomycin exhibits potent activity against Gram positive bacteria and is highly effective against MRSA in vitro and in vivo. Vancomycin interferes with cell wall synthesis by binding to D-alanine-D-alanine residues.

• 一般的な説明

  The isolation of the glycopeptide antibiotic vancomycin(Vancocin, Vancoled) from Streptomyces orientalis (renamedA. orientalis) was described in 1956 by McCormick et al.232The organism originally was obtained from cultures of anIndonesian soil sample and subsequently has been obtainedfrom Indian soil. Vancomycin was introduced in 1958 as anantibiotic active against Gram-positive cocci, particularlystreptococci, staphylococci, and pneumococci. It is not activeagainst Gram-negative bacteria, with the exception ofNeisseria spp. Vancomycin is recommended for use wheninfections fail to respond to treatment with the more commonantibiotics or when the infection is known to be caused by aresistant organism. It is particularly effective for the treatmentof endocarditis caused by Gram-positive bacteria.
  Vancomycin hydrochloride is a free-flowing, tan tobrown powder that is relatively stable in the dry state. It isvery soluble in water and insoluble in organic solvents. Vancomycin inhibits cell wall synthesis by preventingthe synthesis of cell wall mucopeptide polymer. It does soby binding with the D-alanine-D-alanine terminus of theuridine diphosphate-N-acetylmuramyl peptides requiredfor mucopeptide polymerization.236 Details of the bindingwere elucidated by the elegant NMR studies of Williamson.

塩酸バンコマイシン 生産企業

Global(540)Suppliers

塩酸バンコマイシン スペクトルデータ(IR1、IR2、MS)

1404-93-9, 塩酸バンコマイシン キーワード