[D-HIS(BENZYL)6]-LH-RH FRAGMENT 5-9 ETHYLAMIDE TRIFLUOROACETATE SALT

[D-HIS(BENZYL)6]-LH-RH FRAGMENT 5-9 ETHYLAMIDE TRIFLUOROACETATE SALT 化学特性,用途語,生産方法

• Biochem/physiol Actions

  Tyr-His(Bz)-Leu-Arg-Pro-NHEt ([D-His(Bzl)6]-LH-RH Fragment 5-9) is a peptide from GnRH (gonadotropin-releasing hormone) agonist, histerelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Histerelin is used for the treatment of central precocious puberty in children.

[D-HIS(BENZYL)6]-LH-RH FRAGMENT 5-9 ETHYLAMIDE TRIFLUOROACETATE SALT 生産企業

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