ニトロブロモメタン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H272：火災助長のおそれ；酸化性物質

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P210：熱/火花/裸火/高温のもののような着火源から遠ざ けること。－禁煙。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

ニトロブロモメタン 価格

ニトロブロモメタン 化学特性,用途語,生産方法

• 外観

  無色～うすい黄色、液体

• 化学的特性

  Bromonitromethane is a clear yellow liquid, It is a strong oxidizing agent with properties similar to nitromethane.
  Bromonitromethane has been used:
  in production of various protected α-bromo nitroalkane donors (including Fmoc) for use in Umpolung amide synthesis.
  in preparation of (Z)-1-bromo-1-nitroalkenes via sodium iodide-catalyzed Henry reaction.
  in diastereo- and enantioselective cyclopropanation of β,γ-unsaturated a-ketoesters via domino Michael-addition/intramolecular-alkylation strategy.

• 使用

  Bromonitromethane has received considerable attention as a one-carbon synthon for the synthesis of a variety of important organic intermediates.
  Bromonitromethane is a key starting material for the preparation of the broad-spectrum antibiotic trovafloxacin, which contains the interesting 3-azabicyclo[ 3.1.0]hexane ring system.
  it was used in the synthesis of 2-nitrobenzofuran and 2-nitro-2,3-dihydrobenzofuran-3-ols, nitrobenzo­thio-phenes, and nitrothiazoles, polyfunctionalized nitrocyclopropanes. It has also been utilized in the synthesis of 1-bromo-1-nitroalkan-2-ols and aryl nitromethanes. In addition, it could be used as a bromine donor.

• 製造方法

  Bromonitromethane is commercially available and can also be easily prepared according to the procedures reported by Fishwick et al. A typical procedure is as following: freshly distilled nitromethane was stirred at 0℃ and bromine was dropped in 5 seconds. The resulted bromonitromethane could be used without further purification.

ニトロブロモメタン 上流と下流の製品情報

ニトロブロモメタン 生産企業

Global(138)Suppliers

ニトロブロモメタン スペクトルデータ(¹HNMR、¹³CNMR、IR1、Raman)

563-70-2, ニトロブロモメタン キーワード