1,4-ジデオキシ-1,4-イミノ-D-アラビニトール塩酸塩

1,4-ジデオキシ-1,4-イミノ-D-アラビニトール塩酸塩 価格

1,4-ジデオキシ-1,4-イミノ-D-アラビニトール塩酸塩 化学特性,用途語,生産方法

• 外観

  白色～わずかにうすい褐色, 結晶～結晶性粉末

• 溶解性

  水に溶ける。

• 用途

  糖たん白質糖鎖合成過程、生物機能の解析ツール。

• 使用上の注意

  不活性ガス封入

• 説明

  1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC₅₀ = 1.0 μM) and in homogenates of cerebral cortex and cerebellum (IC₅₀s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.

• 使用

  1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.

• 一般的な説明

  1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.

1,4-ジデオキシ-1,4-イミノ-D-アラビニトール塩酸塩 生産企業

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